Title |
CD133-positive hepatocellular carcinoma in an area endemic for hepatitis B virus infection
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Published in |
BMC Cancer, September 2009
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DOI | 10.1186/1471-2407-9-324 |
Pubmed ID | |
Authors |
Chau-Ting Yeh, Chia-Jung Kuo, Ming-Wei Lai, Tse-Ching Chen, Chun-Yen Lin, Ta-Sen Yeh, Wei-Chen Lee |
Abstract |
CD133 was detected in several types of cancers including hepatocellular carcinoma (HCC), which raised the possibility of stem cell origin in a subset of cancers. However, reappearance of embryonic markers in de-differentiated malignant cells was commonly observed. It remained to be elucidated whether CD133-positive HCCs were indeed of stem cell origin or they were just a group of poorly differentiated cells acquiring an embryonic marker. The aim of this study was to investigate the significance of CD133 expression in HCC in an area endemic for hepatitis B virus (HBV) infection to gain insights on this issue. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 21 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 3 | 14% |
Student > Ph. D. Student | 3 | 14% |
Student > Master | 3 | 14% |
Researcher | 2 | 10% |
Student > Bachelor | 1 | 5% |
Other | 3 | 14% |
Unknown | 6 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 7 | 33% |
Agricultural and Biological Sciences | 6 | 29% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 5% |
Nursing and Health Professions | 1 | 5% |
Unknown | 6 | 29% |