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Mendeley readers
Attention Score in Context
| Title |
Presence of the CYP2B6 516G> T polymorphism, increased plasma Efavirenz concentrations and early neuropsychiatric side effects in South African HIV-infected patients
|
|---|---|
| Published in |
AIDS Research and Therapy, August 2010
|
| DOI | 10.1186/1742-6405-7-32 |
| Pubmed ID | |
| Authors |
Verena Gounden, Chantal van Niekerk, Tracy Snyman, Jaya A George |
| Abstract |
The 516G > T polymorphism in exon 4 of the CYP2B6 gene has been associated with increased plasma Efavirenz (EFV) concentrations. EFV concentrations greater than the recommended therapeutic range have been associated with the increased likelihood of developing adverse CNS effects. The aims of this study were to a) determine the presence of the 516G > T and other CYP2B6 exon 4 polymorphisms in a South African group of HIV-infected individuals b) investigate the relationship between the EFV plasma concentrations, the CYP2B6 516G > T polymorphism and the occurrence of CNS related side effects in this group of patients and c) develop and validate a rapid method for determination of EFV in plasma. |
Mendeley readers
The data shown below were compiled from readership statistics for 91 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| South Africa | 2 | 2% |
| Peru | 1 | 1% |
| Nigeria | 1 | 1% |
| Unknown | 87 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 17 | 19% |
| Student > Master | 17 | 19% |
| Student > Bachelor | 10 | 11% |
| Student > Postgraduate | 9 | 10% |
| Researcher | 8 | 9% |
| Other | 14 | 15% |
| Unknown | 16 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 28 | 31% |
| Agricultural and Biological Sciences | 14 | 15% |
| Pharmacology, Toxicology and Pharmaceutical Science | 14 | 15% |
| Biochemistry, Genetics and Molecular Biology | 7 | 8% |
| Nursing and Health Professions | 2 | 2% |
| Other | 9 | 10% |
| Unknown | 17 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 July 2016.
All research outputs
#5,446,629
of 25,373,627 outputs
Outputs from AIDS Research and Therapy
#161
of 637 outputs
Outputs of similar age
#22,518
of 104,205 outputs
Outputs of similar age from AIDS Research and Therapy
#3
of 4 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 637 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.1. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 104,205 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one.