Title |
Higher percentage of CD133+ cells is associated with poor prognosis in colon carcinoma patients with stage IIIB
|
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Published in |
Journal of Translational Medicine, July 2009
|
DOI | 10.1186/1479-5876-7-56 |
Pubmed ID | |
Authors |
Chun-Yan Li, Bao-Xiu Li, Yi Liang, Rui-Qing Peng, Ya Ding, Da-Zhi Xu, Xin Zhang, Zhi-Zhong Pan, De-Sen Wan, Yi-Xin Zeng, Xiao-Feng Zhu, Xiao-Shi Zhang |
Abstract |
Cancer stem cell model suggested that tumor progression is driven by the overpopulation of cancer stem cells and eradicating or inhibiting the symmetric division of cancer stem cells would become the most important therapeutic strategy. However, clinical evidence for this hypothesis is still scarce. To evaluate the overpopulation hypothesis of cancer stem cells the association of percentage of CD133+ tumor cells with clinicopathological parameters in colon cancer was investigated since CD133 is a putative cancer stem cell marker shared by multiple solid tumors. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Iran, Islamic Republic of | 1 | 3% |
Luxembourg | 1 | 3% |
Unknown | 32 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 12 | 35% |
Student > Master | 6 | 18% |
Researcher | 4 | 12% |
Student > Doctoral Student | 2 | 6% |
Student > Bachelor | 2 | 6% |
Other | 3 | 9% |
Unknown | 5 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 10 | 29% |
Medicine and Dentistry | 10 | 29% |
Biochemistry, Genetics and Molecular Biology | 5 | 15% |
Immunology and Microbiology | 1 | 3% |
Unknown | 8 | 24% |