Title |
The CD44+/CD24-phenotype is enriched in basal-like breast tumors
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Published in |
Breast Cancer Research, June 2008
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DOI | 10.1186/bcr2108 |
Pubmed ID | |
Authors |
Gabriella Honeth, Pär-Ola Bendahl, Markus Ringnér, Lao H Saal, Sofia K Gruvberger-Saal, Kristina Lövgren, Dorthe Grabau, Mårten Fernö, Åke Borg, Cecilia Hegardt |
Abstract |
Human breast tumors are heterogeneous and consist of phenotypically diverse cells. Breast cancer cells with a CD44+/CD24- phenotype have been suggested to have tumor-initiating properties with stem cell-like and invasive features, although it is unclear whether their presence within a tumor has clinical implications. There is also a large heterogeneity between tumors, illustrated by reproducible stratification into various subtypes based on gene expression profiles or histopathological features. We have explored the prevalence of cells with different CD44/CD24 phenotypes within breast cancer subtypes. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 3 | 1% |
Spain | 3 | 1% |
Germany | 2 | <1% |
United Kingdom | 2 | <1% |
Brazil | 1 | <1% |
Argentina | 1 | <1% |
India | 1 | <1% |
Portugal | 1 | <1% |
Russia | 1 | <1% |
Other | 0 | 0% |
Unknown | 238 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 54 | 21% |
Researcher | 52 | 21% |
Student > Master | 32 | 13% |
Student > Bachelor | 25 | 10% |
Student > Doctoral Student | 18 | 7% |
Other | 39 | 15% |
Unknown | 33 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 83 | 33% |
Medicine and Dentistry | 56 | 22% |
Biochemistry, Genetics and Molecular Biology | 46 | 18% |
Pharmacology, Toxicology and Pharmaceutical Science | 7 | 3% |
Engineering | 6 | 2% |
Other | 17 | 7% |
Unknown | 38 | 15% |