Title |
Stereotactic ablative radiotherapy for comprehensive treatment of oligometastatic tumors (SABR-COMET): Study protocol for a randomized phase II trial
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Published in |
BMC Cancer, July 2012
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DOI | 10.1186/1471-2407-12-305 |
Pubmed ID | |
Authors |
David A Palma, Cornelis J A Haasbeek, George B Rodrigues, Max Dahele, Michael Lock, Brian Yaremko, Robert Olson, Mitchell Liu, Jason Panarotto, GwendolynHMJ Griffioen, Stewart Gaede, Ben Slotman, Suresh Senan |
Abstract |
Stereotactic ablative radiotherapy (SABR) has emerged as a new treatment option for patients with oligometastatic disease. SABR delivers precise, high-dose, hypofractionated radiotherapy, and achieves excellent rates of local control. Survival outcomes for patients with oligometastatic disease treated with SABR appear promising, but conclusions are limited by patient selection, and the lack of adequate controls in most studies. The goal of this multicenter randomized phase II trial is to assess the impact of a comprehensive oligometastatic SABR treatment program on overall survival and quality of life in patients with up to 5 metastatic cancer lesions, compared to patients who receive standard of care treatment alone. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 2 | 1% |
Spain | 1 | <1% |
Belgium | 1 | <1% |
Unknown | 149 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 20 | 13% |
Researcher | 20 | 13% |
Student > Master | 14 | 9% |
Student > Postgraduate | 13 | 8% |
Student > Ph. D. Student | 12 | 8% |
Other | 37 | 24% |
Unknown | 37 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 76 | 50% |
Physics and Astronomy | 9 | 6% |
Nursing and Health Professions | 7 | 5% |
Biochemistry, Genetics and Molecular Biology | 3 | 2% |
Agricultural and Biological Sciences | 3 | 2% |
Other | 10 | 7% |
Unknown | 45 | 29% |