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The role of surgical treatment in isolated organ recurrence of esophageal cancer—a systematic review of the literature

Overview of attention for article published in World Journal of Surgical Oncology, March 2018
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Title
The role of surgical treatment in isolated organ recurrence of esophageal cancer—a systematic review of the literature
Published in
World Journal of Surgical Oncology, March 2018
DOI 10.1186/s12957-018-1357-y
Pubmed ID
Authors

Dimitrios Schizas, Ioannis I. Lazaridis, Demetrios Moris, Aikaterini Mastoraki, Lazaros-Dimitrios Lazaridis, Diamantis I. Tsilimigras, Nikolaos Charalampakis, Theodore Liakakos

Abstract

Despite the improvements in the early detection and treatment of non-metastatic esophageal cancer, more than half of patients undergoing a curative treatment for esophageal cancer will develop recurrence within three years. The prognosis of these patients is poor. However, a wide range in overall survival has been reported, depending on the pattern of recurrence, and no optimal treatment strategy following recurrence has yet been uniformly accepted. In this article, we aimed to systematically review the literature for the role of surgical resection of metachronous distant metastasis following primary treatment of esophageal cancer. Furthermore, we discuss possible factors that could possibly predict which patients may benefit from a surgical approach. A comprehensive literature search was conducted in PubMed using combinations of keywords. Patients with recurrence may benefit of a multimodality treatment. Regarding the isolated recurrence of esophageal cancer in solid visceral organs, operative intervention has been proposed as a treatment that may offer a survival benefit in an individual basis. No definitive conclusions regarding the potential survival advantage offered by the surgical treatment of solitary recurrent lesions can be drawn. However, recent improvements in surgical treatment and optimization of perioperative management guarantee an acceptable operative risk, making surgical resection of solitary recurrence lesions a considerable therapeutic option. It can be conferred from the available studies that the surgical treatment of isolated recurrence from esophageal cancer may offer a survival benefit for properly selected patients. Prospective, multicenter studies might be useful to gain a better insight into those factors that affect selection of patients to take benefit from an operative intervention.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 37 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 16%
Student > Master 5 14%
Student > Postgraduate 3 8%
Other 3 8%
Student > Bachelor 3 8%
Other 10 27%
Unknown 7 19%
Readers by discipline Count As %
Medicine and Dentistry 21 57%
Biochemistry, Genetics and Molecular Biology 1 3%
Nursing and Health Professions 1 3%
Unspecified 1 3%
Social Sciences 1 3%
Other 3 8%
Unknown 9 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 March 2018.
All research outputs
#18,590,133
of 23,026,672 outputs
Outputs from World Journal of Surgical Oncology
#1,020
of 2,055 outputs
Outputs of similar age
#259,444
of 333,763 outputs
Outputs of similar age from World Journal of Surgical Oncology
#21
of 32 outputs
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