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Assessment into the usage of levetiracetam in a canine epilepsy clinic

Overview of attention for article published in BMC Veterinary Research, February 2015
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)
  • High Attention Score compared to outputs of the same age and source (89th percentile)

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Title
Assessment into the usage of levetiracetam in a canine epilepsy clinic
Published in
BMC Veterinary Research, February 2015
DOI 10.1186/s12917-015-0340-x
Pubmed ID
Authors

Rowena MA Packer, George Nye, Sian Elizabeth Porter, Holger A Volk

Abstract

Retrospective studies can complement information derived from double-blinded randomized trials. There are multiple retrospective studies reporting good efficacy and tolerability of the anti-epileptic drug levetiracetam (LEV) in human patients with epilepsy; however, reports of LEV's tolerability and efficacy in dogs with epilepsy remain limited. The purpose of this retrospective study was to describe the use of LEV in a canine epilepsy clinic and determine the long-term efficacy and tolerability of LEV in veterinary clinical practice. The electronic database of a UK based referral hospital was searched for LEV usage in dogs with seizures. Information and data necessary for the evaluation were obtained from a combination of electronic and written hospital records, the referring veterinary surgeons' records and telephone interviews with dog owners. Only dogs that were reportedly diagnosed with idiopathic epilepsy were included in the study. Fifty-two dogs were included in this retrospective study. Two treatment protocols were recognised; 29 dogs were treated continuously with LEV and 23 dogs received interval or pulse treatment for cluster seizures. LEV treatment resulted in 69% of dogs having a 50% or greater reduction of seizure frequency whilst 15% of all the dogs were completely free from seizures. Seizure frequency reduced significantly in the whole population. No dog was reported to experience life-threatening side effects. Mild side effects were experienced by 46% of dogs and a significantly higher number of these dogs were in the pulse treatment group. The most common side-effects reported were sedation and ataxia. LEV appears to be effective and well tolerated for reduction of seizures.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 123 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 2%
Unknown 121 98%

Demographic breakdown

Readers by professional status Count As %
Other 14 11%
Student > Bachelor 14 11%
Student > Master 12 10%
Student > Doctoral Student 12 10%
Student > Postgraduate 11 9%
Other 27 22%
Unknown 33 27%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 57 46%
Medicine and Dentistry 14 11%
Agricultural and Biological Sciences 6 5%
Neuroscience 5 4%
Engineering 2 2%
Other 5 4%
Unknown 34 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 January 2017.
All research outputs
#4,590,308
of 22,787,797 outputs
Outputs from BMC Veterinary Research
#339
of 3,050 outputs
Outputs of similar age
#67,377
of 352,561 outputs
Outputs of similar age from BMC Veterinary Research
#9
of 89 outputs
Altmetric has tracked 22,787,797 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,050 research outputs from this source. They receive a mean Attention Score of 3.8. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 352,561 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 89 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.