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Structural insights into the inactivation of CRISPR-Cas systems by diverse anti-CRISPR proteins

Overview of attention for article published in BMC Biology, March 2018
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)

Mentioned by

twitter
29 tweeters
patent
2 patents
facebook
1 Facebook page
wikipedia
2 Wikipedia pages

Citations

dimensions_citation
23 Dimensions

Readers on

mendeley
90 Mendeley
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Title
Structural insights into the inactivation of CRISPR-Cas systems by diverse anti-CRISPR proteins
Published in
BMC Biology, March 2018
DOI 10.1186/s12915-018-0504-9
Pubmed ID
Authors

Yuwei Zhu, Fan Zhang, Zhiwei Huang

Abstract

A molecular arms race is progressively being unveiled between prokaryotes and viruses. Prokaryotes utilize CRISPR-mediated adaptive immune systems to kill the invading phages and mobile genetic elements, and in turn, the viruses evolve diverse anti-CRISPR proteins to fight back. The structures of several anti-CRISPR proteins have now been reported, and here we discuss their structural features, with a particular emphasis on topology, to discover their similarities and differences. We summarize the CRISPR-Cas inhibition mechanisms of these anti-CRISPR proteins in their structural context. Considering anti-CRISPRs in this way will provide important clues for studying their origin and evolution.

Twitter Demographics

The data shown below were collected from the profiles of 29 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 90 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 90 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 19 21%
Student > Master 12 13%
Student > Ph. D. Student 11 12%
Researcher 11 12%
Professor > Associate Professor 4 4%
Other 10 11%
Unknown 23 26%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 42 47%
Agricultural and Biological Sciences 12 13%
Immunology and Microbiology 4 4%
Engineering 2 2%
Computer Science 1 1%
Other 4 4%
Unknown 25 28%

Attention Score in Context

This research output has an Altmetric Attention Score of 21. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 April 2020.
All research outputs
#1,184,741
of 18,404,646 outputs
Outputs from BMC Biology
#357
of 1,577 outputs
Outputs of similar age
#31,792
of 287,719 outputs
Outputs of similar age from BMC Biology
#1
of 1 outputs
Altmetric has tracked 18,404,646 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,577 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.2. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 287,719 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them