Title |
Association of DNA methylation with age, gender, and smoking in an Arab population
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Published in |
Clinical Epigenetics, January 2015
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DOI | 10.1186/s13148-014-0040-6 |
Pubmed ID | |
Authors |
Shaza B Zaghlool, Mashael Al-Shafai, Wadha A Al Muftah, Pankaj Kumar, Mario Falchi, Karsten Suhre |
Abstract |
Modification of DNA by methylation of cytosines at CpG dinucleotides is a widespread phenomenon that leads to changes in gene expression, thereby influencing and regulating many biological processes. Recent technical advances in the genome-wide determination of single-base DNA-methylation enabled epigenome-wide association studies (EWASs). Early EWASs established robust associations between age and gender with the degree of CpG methylation at specific sites. Other studies uncovered associations with cigarette smoking. However, so far these studies were mainly conducted in Caucasians, raising the question of whether these findings can also be extrapolated to other populations. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 67% |
Science communicators (journalists, bloggers, editors) | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 1 | <1% |
Switzerland | 1 | <1% |
Brazil | 1 | <1% |
Sweden | 1 | <1% |
New Zealand | 1 | <1% |
Unknown | 118 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 30 | 24% |
Researcher | 19 | 15% |
Student > Master | 18 | 15% |
Student > Bachelor | 11 | 9% |
Student > Doctoral Student | 6 | 5% |
Other | 20 | 16% |
Unknown | 19 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 33 | 27% |
Agricultural and Biological Sciences | 23 | 19% |
Medicine and Dentistry | 22 | 18% |
Computer Science | 6 | 5% |
Environmental Science | 2 | 2% |
Other | 11 | 9% |
Unknown | 26 | 21% |