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Glycogen synthase kinase3 beta phosphorylates serine 33 of p53 and activates p53's transcriptional activity

Overview of attention for article published in BMC Molecular and Cell Biology, July 2001
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3 Wikipedia pages

Citations

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109 Dimensions

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78 Mendeley
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Title
Glycogen synthase kinase3 beta phosphorylates serine 33 of p53 and activates p53's transcriptional activity
Published in
BMC Molecular and Cell Biology, July 2001
DOI 10.1186/1471-2121-2-12
Pubmed ID
Authors

Gaetan A Turenne, Brendan D Price

Abstract

The p53 protein is activated by genotoxic stress, oncogene expression and during senescence, p53 transcriptionally activates genes involved in growth arrest and apoptosis. p53 activation is regulated by post-translational modification, including phosphorylation of the N-terminal transactivation domain. Here, we have examined how Glycogen Synthase Kinase (GSK3), a protein kinase involved in tumorigenesis, differentiation and apoptosis, phosphorylates and regulates p53.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 78 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 3%
Spain 1 1%
Netherlands 1 1%
France 1 1%
Unknown 73 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 23%
Student > Master 12 15%
Student > Bachelor 10 13%
Researcher 8 10%
Student > Postgraduate 5 6%
Other 11 14%
Unknown 14 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 25 32%
Biochemistry, Genetics and Molecular Biology 13 17%
Medicine and Dentistry 7 9%
Chemistry 5 6%
Neuroscience 3 4%
Other 9 12%
Unknown 16 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 April 2024.
All research outputs
#8,534,528
of 25,371,288 outputs
Outputs from BMC Molecular and Cell Biology
#334
of 1,233 outputs
Outputs of similar age
#13,989
of 40,809 outputs
Outputs of similar age from BMC Molecular and Cell Biology
#1
of 7 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,233 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 40,809 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them