↓ Skip to main content

Prevalence and antibiotic resistance of bacteria isolated from the cerebrospinal fluid of neurosurgical patients at Peking Union Medical College Hospital

Overview of attention for article published in Antimicrobial Resistance and Infection Control, March 2018
Altmetric Badge

About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (64th percentile)

Mentioned by

twitter
8 tweeters

Citations

dimensions_citation
18 Dimensions

Readers on

mendeley
42 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Prevalence and antibiotic resistance of bacteria isolated from the cerebrospinal fluid of neurosurgical patients at Peking Union Medical College Hospital
Published in
Antimicrobial Resistance and Infection Control, March 2018
DOI 10.1186/s13756-018-0323-3
Pubmed ID
Authors

Jian-bo Chang, Hao Wu, He Wang, Bai-tao Ma, Ren-zhi Wang, Jun-ji Wei

Abstract

Postoperative central nervous system infections (PCNSIs) represent a serious complication, and the timely use of antibiotics guided by the identification of the causative pathogens and their antibiotic sensitivities is essential for treatment. However, there are little data regarding the prevalence of PCNSI pathogens in China. The aim of this study is to investigate the features of pathogens in patients with PCNSIs, which could help clinicians to choose the appropriate empirical antibiotic therapy. We retrospectively examined the positive CSF cultures in patients who underwent craniotomy between January 2010 and December 2015. We collected data, including demographic characteristics, type of neurosurgery, laboratory data, causative organisms and antimicrobial susceptibility testing results. A total of 62 patients with 90 isolates out of 818 patients with 2433 CSF culture samples were available for data analysis. The estimated incidence and culture-positive rate of PCNSIs were approximately 0.9 and 7.5%, respectively. The predominant organism was coagulase-negative staphylococci, of which most were methicillin-resistant coagulase-negative staphylococci (MRCoNS). All were susceptible to vancomycin, linezolid, rifampicin and amoxicillin-clavulanate.Acinetobacter baumanniiwas the most frequent causative Gram-negative agent and was resistant to 12 out of 18 antimicrobials tested. The sensitivity rates for tigecycline and minocycline were only 40 and 33%, respectively. PCNSIs could lead to high mortality. Although the MRCoNS were the predominant organism, the management ofAcinetobacter baumanniiwas a major clinical challenge with few effective antimicrobials in PCNSIs.

Twitter Demographics

The data shown below were collected from the profiles of 8 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 42 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 17%
Student > Doctoral Student 5 12%
Student > Bachelor 5 12%
Student > Postgraduate 5 12%
Student > Master 4 10%
Other 5 12%
Unknown 11 26%
Readers by discipline Count As %
Medicine and Dentistry 17 40%
Pharmacology, Toxicology and Pharmaceutical Science 4 10%
Arts and Humanities 3 7%
Immunology and Microbiology 3 7%
Veterinary Science and Veterinary Medicine 1 2%
Other 3 7%
Unknown 11 26%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 April 2018.
All research outputs
#5,857,186
of 19,831,185 outputs
Outputs from Antimicrobial Resistance and Infection Control
#561
of 1,115 outputs
Outputs of similar age
#104,847
of 295,000 outputs
Outputs of similar age from Antimicrobial Resistance and Infection Control
#1
of 1 outputs
Altmetric has tracked 19,831,185 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 1,115 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 16.2. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 295,000 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them