↓ Skip to main content

Construction and analysis of a modular model of caspase activation in apoptosis

Overview of attention for article published in Theoretical Biology and Medical Modelling, December 2008
Altmetric Badge

Mentioned by

wikipedia
6 Wikipedia pages

Citations

dimensions_citation
93 Dimensions

Readers on

mendeley
105 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Construction and analysis of a modular model of caspase activation in apoptosis
Published in
Theoretical Biology and Medical Modelling, December 2008
DOI 10.1186/1742-4682-5-26
Pubmed ID
Authors

Heather A Harrington, Kenneth L Ho, Samik Ghosh, KC Tung

Abstract

A key physiological mechanism employed by multicellular organisms is apoptosis, or programmed cell death. Apoptosis is triggered by the activation of caspases in response to both extracellular (extrinsic) and intracellular (intrinsic) signals. The extrinsic and intrinsic pathways are characterized by the formation of the death-inducing signaling complex (DISC) and the apoptosome, respectively; both the DISC and the apoptosome are oligomers with complex formation dynamics. Additionally, the extrinsic and intrinsic pathways are coupled through the mitochondrial apoptosis-induced channel via the Bcl-2 family of proteins.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 105 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
Gambia 1 <1%
Unknown 102 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 21 20%
Researcher 18 17%
Student > Master 18 17%
Student > Bachelor 11 10%
Student > Doctoral Student 4 4%
Other 15 14%
Unknown 18 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 25 24%
Biochemistry, Genetics and Molecular Biology 14 13%
Medicine and Dentistry 11 10%
Engineering 9 9%
Chemistry 5 5%
Other 18 17%
Unknown 23 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 February 2024.
All research outputs
#7,731,211
of 23,515,785 outputs
Outputs from Theoretical Biology and Medical Modelling
#98
of 284 outputs
Outputs of similar age
#48,318
of 167,944 outputs
Outputs of similar age from Theoretical Biology and Medical Modelling
#1
of 2 outputs
Altmetric has tracked 23,515,785 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 284 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.5. This one has gotten more attention than average, scoring higher than 57% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 167,944 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 19th percentile – i.e., 19% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them