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Adoptive cell therapy with autologous tumor infiltrating lymphocytes and low-dose Interleukin-2 in metastatic melanoma patients

Overview of attention for article published in Journal of Translational Medicine, August 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (89th percentile)
  • High Attention Score compared to outputs of the same age and source (86th percentile)

Mentioned by

patent
5 patents
wikipedia
5 Wikipedia pages

Citations

dimensions_citation
139 Dimensions

Readers on

mendeley
196 Mendeley
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Title
Adoptive cell therapy with autologous tumor infiltrating lymphocytes and low-dose Interleukin-2 in metastatic melanoma patients
Published in
Journal of Translational Medicine, August 2012
DOI 10.1186/1479-5876-10-169
Pubmed ID
Authors

Eva Ellebaek, Trine Zeeberg Iversen, Niels Junker, Marco Donia, Lotte Engell-Noerregaard, Özcan Met, Lisbet Rosenkrantz Hölmich, Rikke Sick Andersen, Sine Reker Hadrup, Mads Hald Andersen, Per thor Straten, Inge Marie Svane

Abstract

Adoptive cell therapy may be based on isolation of tumor-specific T cells, e.g. autologous tumor infiltrating lymphocytes (TIL), in vitro activation and expansion and the reinfusion of these cells into patients upon chemotherapy induced lymphodepletion. Together with high-dose interleukin (IL)-2 this treatment has been given to patients with advanced malignant melanoma and impressive response rates but also significant IL-2 associated toxicity have been observed. Here we present data from a feasibility study at a Danish Translational Research Center using TIL adoptive transfer in combination with low-dose subcutaneous IL-2 injections.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 196 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 <1%
Denmark 1 <1%
France 1 <1%
Unknown 193 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 38 19%
Researcher 35 18%
Student > Master 32 16%
Student > Bachelor 16 8%
Other 13 7%
Other 18 9%
Unknown 44 22%
Readers by discipline Count As %
Medicine and Dentistry 50 26%
Agricultural and Biological Sciences 45 23%
Immunology and Microbiology 21 11%
Biochemistry, Genetics and Molecular Biology 19 10%
Pharmacology, Toxicology and Pharmaceutical Science 3 2%
Other 10 5%
Unknown 48 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 September 2023.
All research outputs
#2,564,518
of 23,510,717 outputs
Outputs from Journal of Translational Medicine
#418
of 4,167 outputs
Outputs of similar age
#17,210
of 170,349 outputs
Outputs of similar age from Journal of Translational Medicine
#7
of 53 outputs
Altmetric has tracked 23,510,717 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,167 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.6. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 170,349 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 53 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.