Title |
MicroRNA-296: a promising target in the pathogenesis of atherosclerosis?
|
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Published in |
Molecular Medicine, March 2018
|
DOI | 10.1186/s10020-018-0012-y |
Pubmed ID | |
Authors |
Heng Li, Xin-Ping Ouyang, Ting Jiang, Xi-Long Zheng, Ping-Ping He, Guo-Jun Zhao |
Abstract |
Atherosclerosis has been recognized as an inflammatory disease involving the vascular wall. MicroRNAs are a group of small noncoding RNAs to regulate gene expression at the transcriptional level through mRNA degradation or translation repression. Recent studies suggest that miR-296 may play crucial roles in the regulation of angiogenesis, inflammatory response, cholesterol metabolism, hypertension, cellular proliferation and apoptosis. In this review, we primarily discussed the molecular targets of miR-296 involved in the development of atherosclerosis, which may provide a basis for future investigation and a better understanding of the biological functions of miR-296 in atherosclerosis. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 40 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 5 | 13% |
Researcher | 5 | 13% |
Student > Master | 5 | 13% |
Student > Bachelor | 2 | 5% |
Professor | 2 | 5% |
Other | 8 | 20% |
Unknown | 13 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 8 | 20% |
Medicine and Dentistry | 5 | 13% |
Agricultural and Biological Sciences | 3 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 5% |
Materials Science | 2 | 5% |
Other | 4 | 10% |
Unknown | 16 | 40% |