Title |
Analysis of the regulation of fatty acid binding protein 7 expression in human renal carcinoma cell lines
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Published in |
BMC Molecular and Cell Biology, July 2011
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DOI | 10.1186/1471-2199-12-31 |
Pubmed ID | |
Authors |
Naohisa Takaoka, Tatsuya Takayama, Takumi Teratani, Takayuki Sugiyama, Soichi Mugiya, Seiichiro Ozono |
Abstract |
Improving the treatment of renal cell carcinoma (RCC) will depend on the development of better biomarkers for predicting disease progression and aiding the design of appropriate therapies. One such marker may be fatty acid binding protein 7 (FABP7), also known as B-FABP and BLBP, which is expressed normally in radial glial cells of the developing central nervous system and cells of the mammary gland. Melanomas, glioblastomas, and several types of carcinomas, including RCC, overexpress FABP7. The abundant expression of FABP7 in primary RCCs compared to certain RCC-derived cell lines may allow the definition of the molecular components of FABP7's regulatory system. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 1 | 3% |
Unknown | 28 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 8 | 28% |
Student > Bachelor | 5 | 17% |
Student > Master | 3 | 10% |
Student > Doctoral Student | 2 | 7% |
Other | 2 | 7% |
Other | 6 | 21% |
Unknown | 3 | 10% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 10 | 34% |
Biochemistry, Genetics and Molecular Biology | 5 | 17% |
Medicine and Dentistry | 4 | 14% |
Unspecified | 2 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
Other | 4 | 14% |
Unknown | 3 | 10% |