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Inhibition of Tat activity by the HEXIM1 protein

Overview of attention for article published in Retrovirology, July 2005
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3 Wikipedia pages

Citations

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33 Dimensions

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24 Mendeley
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Title
Inhibition of Tat activity by the HEXIM1 protein
Published in
Retrovirology, July 2005
DOI 10.1186/1742-4690-2-42
Pubmed ID
Authors

Alessandro Fraldi, Francesca Varrone, Giuliana Napolitano, Annemieke A Michels, Barbara Majello, Olivier Bensaude, Luigi Lania

Abstract

The positive transcription elongation factor b (P-TEFb) composed by CDK9/CyclinT1 subunits is a dedicated co-factor of HIV transcriptional transactivator Tat protein. Transcription driven by the long terminal repeat (LTR) of HIV involves formation of a quaternary complex between P-TEFb, Tat and the TAR element. This recruitment is necessary to enhance the processivity of RNA Pol II from the HIV-1 5' LTR promoter. The activity of P-TEFb is regulated in vivo and in vitro by the HEXIM1/7SK snRNA ribonucleic-protein complex.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 1 4%
Canada 1 4%
Switzerland 1 4%
Unknown 21 88%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 21%
Student > Bachelor 4 17%
Student > Ph. D. Student 4 17%
Professor 3 13%
Other 2 8%
Other 5 21%
Unknown 1 4%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 50%
Biochemistry, Genetics and Molecular Biology 5 21%
Chemistry 2 8%
Business, Management and Accounting 1 4%
Veterinary Science and Veterinary Medicine 1 4%
Other 2 8%
Unknown 1 4%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 July 2018.
All research outputs
#7,454,066
of 22,788,370 outputs
Outputs from Retrovirology
#408
of 1,106 outputs
Outputs of similar age
#20,174
of 56,731 outputs
Outputs of similar age from Retrovirology
#3
of 4 outputs
Altmetric has tracked 22,788,370 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,106 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has gotten more attention than average, scoring higher than 51% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 56,731 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one.