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Inhibition of Tat activity by the HEXIM1 protein

Overview of attention for article published in Retrovirology, July 2005
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (66th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (55th percentile)

Mentioned by

wikipedia
1 Wikipedia page

Citations

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31 Dimensions

Readers on

mendeley
21 Mendeley
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Title
Inhibition of Tat activity by the HEXIM1 protein
Published in
Retrovirology, July 2005
DOI 10.1186/1742-4690-2-42
Pubmed ID
Authors

Alessandro Fraldi, Francesca Varrone, Giuliana Napolitano, Annemieke A Michels, Barbara Majello, Olivier Bensaude, Luigi Lania

Abstract

The positive transcription elongation factor b (P-TEFb) composed by CDK9/CyclinT1 subunits is a dedicated co-factor of HIV transcriptional transactivator Tat protein. Transcription driven by the long terminal repeat (LTR) of HIV involves formation of a quaternary complex between P-TEFb, Tat and the TAR element. This recruitment is necessary to enhance the processivity of RNA Pol II from the HIV-1 5' LTR promoter. The activity of P-TEFb is regulated in vivo and in vitro by the HEXIM1/7SK snRNA ribonucleic-protein complex.

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 1 5%
Canada 1 5%
Switzerland 1 5%
Unknown 18 86%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 24%
Student > Bachelor 4 19%
Student > Ph. D. Student 3 14%
Professor 3 14%
Professor > Associate Professor 2 10%
Other 4 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 57%
Biochemistry, Genetics and Molecular Biology 5 24%
Chemistry 2 10%
Social Sciences 1 5%
Business, Management and Accounting 1 5%
Other 0 0%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 January 2008.
All research outputs
#3,618,343
of 12,472,057 outputs
Outputs from Retrovirology
#213
of 715 outputs
Outputs of similar age
#79,190
of 271,268 outputs
Outputs of similar age from Retrovirology
#4
of 9 outputs
Altmetric has tracked 12,472,057 research outputs across all sources so far. This one is in the 49th percentile – i.e., 49% of other outputs scored the same or lower than it.
So far Altmetric has tracked 715 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.8. This one has gotten more attention than average, scoring higher than 57% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 271,268 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.