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Central pathways causing fatigue in neuro-inflammatory and autoimmune illnesses

Overview of attention for article published in BMC Medicine, February 2015
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (97th percentile)
  • Good Attention Score compared to outputs of the same age and source (79th percentile)

Mentioned by

twitter
83 X users
facebook
32 Facebook pages
googleplus
1 Google+ user
reddit
1 Redditor
video
1 YouTube creator

Citations

dimensions_citation
136 Dimensions

Readers on

mendeley
354 Mendeley
citeulike
1 CiteULike
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Title
Central pathways causing fatigue in neuro-inflammatory and autoimmune illnesses
Published in
BMC Medicine, February 2015
DOI 10.1186/s12916-014-0259-2
Pubmed ID
Authors

Gerwyn Morris, Michael Berk, Ken Walder, Michael Maes

Abstract

The genesis of severe fatigue and disability in people following acute pathogen invasion involves the activation of Toll-like receptors followed by the upregulation of proinflammatory cytokines and the activation of microglia and astrocytes. Many patients suffering from neuroinflammatory and autoimmune diseases, such as multiple sclerosis, Parkinson's disease and systemic lupus erythematosus, also commonly suffer from severe disabling fatigue. Such patients also present with chronic peripheral immune activation and systemic inflammation in the guise of elevated proinflammtory cytokines, oxidative stress and activated Toll-like receptors. This is also true of many patients presenting with severe, apparently idiopathic, fatigue accompanied by profound levels of physical and cognitive disability often afforded the non-specific diagnosis of chronic fatigue syndrome.

X Demographics

X Demographics

The data shown below were collected from the profiles of 83 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 354 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 <1%
United States 2 <1%
Spain 1 <1%
India 1 <1%
Unknown 348 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 59 17%
Student > Master 56 16%
Student > Ph. D. Student 43 12%
Student > Bachelor 39 11%
Other 24 7%
Other 68 19%
Unknown 65 18%
Readers by discipline Count As %
Medicine and Dentistry 93 26%
Agricultural and Biological Sciences 33 9%
Nursing and Health Professions 32 9%
Neuroscience 32 9%
Biochemistry, Genetics and Molecular Biology 20 6%
Other 71 20%
Unknown 73 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 58. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 April 2023.
All research outputs
#739,304
of 25,654,806 outputs
Outputs from BMC Medicine
#517
of 4,067 outputs
Outputs of similar age
#9,584
of 362,304 outputs
Outputs of similar age from BMC Medicine
#12
of 58 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,067 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 45.9. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 362,304 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 79% of its contemporaries.