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Gata-3 and mammary cell fate

Overview of attention for article published in Breast Cancer Research, January 2007
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Title
Gata-3 and mammary cell fate
Published in
Breast Cancer Research, January 2007
DOI 10.1186/bcr1661
Pubmed ID
Authors

Matthew J Naylor, Christopher J Ormandy, Naylor MJ, Ormandy CJ

Abstract

Genomic regulatory networks specify how cellular gene expression responds to external temporal and spatial stimuli, ensuring that correct cell fate decisions are made and the appropriate cell phenotypes are adopted. In mammary epithelial cells, the hierarchy of stem and progenitor cells and the genetically specified program of transcriptional activity are beginning to be elucidated and integrated. A novel role for Gata-3 in specifying and maintaining mammary cell fate has recently been identified. These reports offer an understanding of how mammary cells assume and maintain a variety of cell behaviours and functions, and how a mammary cell may potentially subvert these constraints during carcinogenesis.

Mendeley readers

The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 8%
Argentina 1 8%
Unknown 11 85%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 31%
Student > Bachelor 3 23%
Professor 1 8%
Student > Ph. D. Student 1 8%
Lecturer > Senior Lecturer 1 8%
Other 1 8%
Unknown 2 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 10 77%
Biochemistry, Genetics and Molecular Biology 1 8%
Unknown 2 15%