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Mendeley readers
Attention Score in Context
Title |
Signalling crosstalk in FGF2-mediated protection of endothelial cells from HIV-gp120
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Published in |
BMC Neuroscience, February 2005
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DOI | 10.1186/1471-2202-6-8 |
Pubmed ID | |
Authors |
Dianne Langford, Rosemary Hurford, Makoto Hashimoto, Murat Digicaylioglu, Eliezer Masliah |
Abstract |
The blood brain barrier (BBB) is the first line of defence of the central nervous system (CNS) against circulating pathogens, such as HIV. The cytotoxic HIV protein, gp120, damages endothelial cells of the BBB, thereby compromising its integrity, which may lead to migration of HIV-infected cells into the brain. Fibroblast growth factor 2 (FGF2), produced primarily by astrocytes, promotes endothelial cell fitness and angiogenesis. We hypothesized that treatment of human umbilical vein endothelial cells (HUVEC) with FGF2 would protect the cells from gp120-mediated toxicity via endothelial cell survival signalling. |
Mendeley readers
The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 4% |
Unknown | 23 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 5 | 21% |
Professor > Associate Professor | 3 | 13% |
Researcher | 3 | 13% |
Student > Bachelor | 3 | 13% |
Other | 2 | 8% |
Other | 3 | 13% |
Unknown | 5 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 6 | 25% |
Medicine and Dentistry | 5 | 21% |
Biochemistry, Genetics and Molecular Biology | 3 | 13% |
Neuroscience | 2 | 8% |
Chemistry | 1 | 4% |
Other | 1 | 4% |
Unknown | 6 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 July 2018.
All research outputs
#8,534,528
of 25,371,288 outputs
Outputs from BMC Neuroscience
#395
of 1,294 outputs
Outputs of similar age
#40,968
of 158,206 outputs
Outputs of similar age from BMC Neuroscience
#3
of 6 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,294 research outputs from this source. They receive a mean Attention Score of 4.7. This one has gotten more attention than average, scoring higher than 60% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 158,206 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.