↓ Skip to main content

Requirements for activation and RAFT localization of the T-lymphocyte kinase Rlk/Txk

Overview of attention for article published in BMC Immunology, May 2001
Altmetric Badge

Mentioned by

wikipedia
2 Wikipedia pages

Citations

dimensions_citation
40 Dimensions

Readers on

mendeley
22 Mendeley
citeulike
1 CiteULike
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Requirements for activation and RAFT localization of the T-lymphocyte kinase Rlk/Txk
Published in
BMC Immunology, May 2001
DOI 10.1186/1471-2172-2-3
Pubmed ID
Authors

Mario Chamorro, Michael J Czar, Jayanta Debnath, Genhong Cheng, Michael J Lenardo, Harold E Varmus, Pamela L Schwartzberg

Abstract

The Tec family kinases are implicated in signaling from lymphocyte antigen receptors and are activated following phosphorylation by Src kinases. For most Tec kinases, this activation requires an interaction between their pleckstrin homology (PH) domains and the products of phosphoinositide 3-Kinase, which localizes Tec kinases to membrane RAFTs. Rlk/Txk is a Tec related kinase expressed in T cells that lacks a pleckstrin homology domain, having instead a palmitoylated cysteine-string motif. To evaluate Rlk's function in T cell receptor signaling cascades, we examined the requirements for Rlk localization and activation by Src family kinases.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 22 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 41%
Student > Ph. D. Student 4 18%
Other 2 9%
Student > Doctoral Student 2 9%
Student > Bachelor 1 5%
Other 1 5%
Unknown 3 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 10 45%
Biochemistry, Genetics and Molecular Biology 3 14%
Medicine and Dentistry 2 9%
Immunology and Microbiology 1 5%
Engineering 1 5%
Other 0 0%
Unknown 5 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 November 2017.
All research outputs
#8,535,472
of 25,374,917 outputs
Outputs from BMC Immunology
#159
of 624 outputs
Outputs of similar age
#14,291
of 42,404 outputs
Outputs of similar age from BMC Immunology
#1
of 1 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 624 research outputs from this source. They receive a mean Attention Score of 3.8. This one has gotten more attention than average, scoring higher than 63% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 42,404 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them