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Plasma nesfatin-1 level is associated with severity of depression in Chinese depressive patients

Overview of attention for article published in BMC Psychiatry, April 2018
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  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (69th percentile)

Mentioned by

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1 blog
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1 Facebook page

Citations

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30 Dimensions

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28 Mendeley
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Title
Plasma nesfatin-1 level is associated with severity of depression in Chinese depressive patients
Published in
BMC Psychiatry, April 2018
DOI 10.1186/s12888-018-1672-4
Pubmed ID
Authors

Min-Min Xiao, Jiang-Bo Li, Lan-Lan Jiang, Hui Shao, Bao-Long Wang

Abstract

Nesfatin-1 plays a role in the regulation of emotional states like depression. The aim of this study was to investigate the plasma nesfatin-1levels in Chinese patients with depression and healthy subjects, and to determine the possible association between the plasma nesfatin-1 level and the severity of depression. A total of 103 depressive patients and 32 healthy subjects were assessed. According to HAMD-17scores, 51, 18, and 34 patients were enrolled in the mild depression, moderate depression, and severe depression groups, respectively. Plasma nesfatin-1 levels were determined by the ELISA method. Differences between groups were compared and associations between plasma nesfatin-1 and other variables were analyzed. The plasma nesfatin-1 was significantly positively correlated with HAMD-17 score (r = 0.651). Compared with healthy controls (8.11 ± 3.31 ng/mL), the plasma nesfatin-1 level significantly increased in patients with mild depression (11.17 ± 3.58 ng/mL), with moderate depression (16.33 ± 8.78 ng/mL), and with severe depression (27.65 ± 8.26 ng/mL) respectively. Plasma nesfatin-1 level (Odds ratio [OR] = 1.269) was an independent indicator for severe depression by multivariate logistic regression analysis. The plasma nesfatin-1 level is positively correlated with the severity of depression. Plasma nesfatin-1 level may be a potential indicator for depression severity.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 28 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 25%
Student > Bachelor 4 14%
Researcher 3 11%
Student > Doctoral Student 2 7%
Student > Postgraduate 2 7%
Other 0 0%
Unknown 10 36%
Readers by discipline Count As %
Medicine and Dentistry 5 18%
Psychology 3 11%
Biochemistry, Genetics and Molecular Biology 2 7%
Agricultural and Biological Sciences 1 4%
Veterinary Science and Veterinary Medicine 1 4%
Other 2 7%
Unknown 14 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 April 2018.
All research outputs
#5,699,160
of 23,035,022 outputs
Outputs from BMC Psychiatry
#1,912
of 4,752 outputs
Outputs of similar age
#99,278
of 329,113 outputs
Outputs of similar age from BMC Psychiatry
#57
of 91 outputs
Altmetric has tracked 23,035,022 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,752 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.9. This one has gotten more attention than average, scoring higher than 57% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,113 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 91 others from the same source and published within six weeks on either side of this one. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.