Title |
Expression of FOXA1 and GATA-3 in breast cancer: the prognostic significance in hormone receptor-negative tumours
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Published in |
Breast Cancer Research, June 2009
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DOI | 10.1186/bcr2327 |
Pubmed ID | |
Authors |
André Albergaria, Joana Paredes, Bárbara Sousa, Fernanda Milanezi, Vítor Carneiro, Joana Bastos, Sandra Costa, Daniella Vieira, Nair Lopes, Eric W Lam, Nuno Lunet, Fernando Schmitt |
Abstract |
The expression of additional genes, other than oestrogen receptor (ER), may be important to the hormone-responsive phenotype of breast cancer. Microarray analyses have revealed that forkhead box A1 (FOXA1) and GATA binding protein 3 (GATA-3) are expressed in close association with ERalpha, both encoding for transcription factors with a potential involvement in the ERalpha-mediated action in breast cancer. The purpose of this study was to explore if the expression of FOXA1 and GATA-3 may provide an opportunity to stratify subsets of patients that could have better outcome, among the ERalpha-negative/poor prognosis breast cancer group. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Portugal | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 2% |
Portugal | 1 | <1% |
Malaysia | 1 | <1% |
Brazil | 1 | <1% |
Netherlands | 1 | <1% |
Iran, Islamic Republic of | 1 | <1% |
United Kingdom | 1 | <1% |
Unknown | 109 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 22 | 19% |
Student > Master | 20 | 17% |
Student > Ph. D. Student | 16 | 14% |
Student > Bachelor | 12 | 10% |
Professor > Associate Professor | 7 | 6% |
Other | 20 | 17% |
Unknown | 20 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 39 | 33% |
Biochemistry, Genetics and Molecular Biology | 21 | 18% |
Medicine and Dentistry | 21 | 18% |
Computer Science | 5 | 4% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 2% |
Other | 8 | 7% |
Unknown | 21 | 18% |