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X Demographics
Mendeley readers
Attention Score in Context
| Title |
PhyloWGS: Reconstructing subclonal composition and evolution from whole-genome sequencing of tumors
|
|---|---|
| Published in |
Genome Biology, February 2015
|
| DOI | 10.1186/s13059-015-0602-8 |
| Pubmed ID | |
| Authors |
Amit G Deshwar, Shankar Vembu, Christina K Yung, Gun Ho Jang, Lincoln Stein, Quaid Morris |
| Abstract |
Tumors often contain multiple subpopulations of cancerous cells defined by distinct somatic mutations. We describe a new method, PhyloWGS, which can be applied to whole-genome sequencing data from one or more tumor samples to reconstruct complete genotypes of these subpopulations based on variant allele frequencies (VAFs) of point mutations and population frequencies of structural variations. We introduce a principled phylogenic correction for VAFs in loci affected by copy number alterations and we show that this correction greatly improves subclonal reconstruction compared to existing methods. PhyloWGS is free, open-source software, available at https://github.com/morrislab/phylowgs. |
X Demographics
The data shown below were collected from the profiles of 32 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 6 | 19% |
| United States | 6 | 19% |
| India | 3 | 9% |
| Canada | 3 | 9% |
| Australia | 2 | 6% |
| Austria | 1 | 3% |
| Japan | 1 | 3% |
| Unknown | 10 | 31% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 20 | 63% |
| Members of the public | 10 | 31% |
| Science communicators (journalists, bloggers, editors) | 1 | 3% |
| Practitioners (doctors, other healthcare professionals) | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 454 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 12 | 3% |
| Germany | 2 | <1% |
| Italy | 2 | <1% |
| Sweden | 2 | <1% |
| Canada | 2 | <1% |
| United Kingdom | 2 | <1% |
| Korea, Republic of | 1 | <1% |
| Ghana | 1 | <1% |
| Spain | 1 | <1% |
| Other | 1 | <1% |
| Unknown | 428 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 112 | 25% |
| Researcher | 108 | 24% |
| Student > Bachelor | 42 | 9% |
| Student > Master | 38 | 8% |
| Student > Doctoral Student | 24 | 5% |
| Other | 60 | 13% |
| Unknown | 70 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 121 | 27% |
| Agricultural and Biological Sciences | 118 | 26% |
| Computer Science | 53 | 12% |
| Medicine and Dentistry | 26 | 6% |
| Mathematics | 21 | 5% |
| Other | 39 | 9% |
| Unknown | 76 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 29. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 December 2021.
All research outputs
#1,331,530
of 25,371,288 outputs
Outputs from Genome Biology
#1,037
of 4,467 outputs
Outputs of similar age
#18,708
of 368,290 outputs
Outputs of similar age from Genome Biology
#17
of 65 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 368,290 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 65 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.