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The C(-1019)G 5-HT1A promoter polymorphism and personality traits: no evidence for significant association in alcoholic patients

Overview of attention for article published in Behavioral and Brain Functions, February 2006
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  • Good Attention Score compared to outputs of the same age and source (66th percentile)

Mentioned by

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1 Wikipedia page

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27 Mendeley
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Title
The C(-1019)G 5-HT1A promoter polymorphism and personality traits: no evidence for significant association in alcoholic patients
Published in
Behavioral and Brain Functions, February 2006
DOI 10.1186/1744-9081-2-7
Pubmed ID
Authors

G Koller, B Bondy, UW Preuss, P Zill, M Soyka

Abstract

The 5HT1A receptor is one of at least 14 different receptors for serotonin which has a role in moderating several brain functions and may be involved in the aetiology of several psychiatric disorders. The C(-1019)G 5-HT1A promoter polymorphism was reported to be associated with major depression, depression-related personality traits and suicidal behavior in various samples. The G(-1019) allele carriers are prone to depressive personality traits and suicidal behavior, because serotonergic neurotransmission is reduced. The aim of this study is to replicate previous findings in a sample of 185 Alcohol-dependent individuals. Personality traits were evaluated using the NEO FFI and TCI. History of suicidal behavior was assessed by a standardized semistructured interview (SSAGA). No significant differences across C(-1019)G 5-HT1A genotype groups were found for TCI temperament and character traits and for NEO FFI personality scales. No association was detected between this genetic variant and history of suicide attempts. These results neither support a role of C(-1019)G 5-HT1A promoter polymorphism in the disposition of personality traits like harm avoidance or neuroticism, nor confirm previous research reporting an involvement of the G allele in suicidal behavior in alcoholics. Significant associations, however, were detected between Babor's Type B with number of suicide attempts in history, high neuroticism and harm avoidance scores in alcoholics.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 2 7%
South Africa 1 4%
Unknown 24 89%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 19%
Researcher 3 11%
Student > Doctoral Student 3 11%
Student > Bachelor 3 11%
Professor 2 7%
Other 7 26%
Unknown 4 15%
Readers by discipline Count As %
Psychology 7 26%
Agricultural and Biological Sciences 6 22%
Medicine and Dentistry 3 11%
Social Sciences 2 7%
Nursing and Health Professions 1 4%
Other 2 7%
Unknown 6 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 September 2008.
All research outputs
#7,454,298
of 22,789,076 outputs
Outputs from Behavioral and Brain Functions
#137
of 391 outputs
Outputs of similar age
#24,582
of 71,579 outputs
Outputs of similar age from Behavioral and Brain Functions
#2
of 9 outputs
Altmetric has tracked 22,789,076 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 391 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.9. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 71,579 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 7 of them.