Title |
A survey of DNA motif finding algorithms
|
---|---|
Published in |
BMC Bioinformatics, November 2007
|
DOI | 10.1186/1471-2105-8-s7-s21 |
Pubmed ID | |
Authors |
Modan K Das, Ho-Kwok Dai |
Abstract |
Unraveling the mechanisms that regulate gene expression is a major challenge in biology. An important task in this challenge is to identify regulatory elements, especially the binding sites in deoxyribonucleic acid (DNA) for transcription factors. These binding sites are short DNA segments that are called motifs. Recent advances in genome sequence availability and in high-throughput gene expression analysis technologies have allowed for the development of computational methods for motif finding. As a result, a large number of motif finding algorithms have been implemented and applied to various motif models over the past decade. This survey reviews the latest developments in DNA motif finding algorithms. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 19 | 3% |
United Kingdom | 11 | 2% |
Spain | 5 | <1% |
Germany | 4 | <1% |
France | 4 | <1% |
China | 3 | <1% |
Canada | 3 | <1% |
Australia | 3 | <1% |
Finland | 3 | <1% |
Other | 31 | 5% |
Unknown | 573 | 87% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 204 | 31% |
Researcher | 140 | 21% |
Student > Master | 98 | 15% |
Student > Bachelor | 47 | 7% |
Professor > Associate Professor | 32 | 5% |
Other | 75 | 11% |
Unknown | 63 | 10% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 311 | 47% |
Computer Science | 124 | 19% |
Biochemistry, Genetics and Molecular Biology | 94 | 14% |
Engineering | 13 | 2% |
Physics and Astronomy | 7 | 1% |
Other | 34 | 5% |
Unknown | 76 | 12% |