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Resistance to ursodeoxycholic acid-induced growth arrest can also result in resistance to deoxycholic acid-induced apoptosis and increased tumorgenicity

Overview of attention for article published in BMC Cancer, September 2006
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  • Good Attention Score compared to outputs of the same age (72nd percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

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1 Wikipedia page

Citations

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22 Dimensions

Readers on

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12 Mendeley
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Title
Resistance to ursodeoxycholic acid-induced growth arrest can also result in resistance to deoxycholic acid-induced apoptosis and increased tumorgenicity
Published in
BMC Cancer, September 2006
DOI 10.1186/1471-2407-6-219
Pubmed ID
Authors

Ashley A Powell, Sandeep Akare, Wenqing Qi, Pascal Herzer, Samira Jean-Louis, Rebecca A Feldman, Jesse D Martinez

Abstract

There is a large body of evidence which suggests that bile acids increase the risk of colon cancer and act as tumor promoters, however, the mechanism(s) of bile acids mediated tumorigenesis is not clear. Previously we showed that deoxycholic acid (DCA), a tumorogenic bile acid, and ursodeoxycholic acid (UDCA), a putative chemopreventive agent, exhibited distinct biological effects, yet appeared to act on some of the same signaling molecules. The present study was carried out to determine whether there is overlap in signaling pathways activated by tumorogenic bile acid DCA and chemopreventive bile acid UDCA.

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 8%
Unknown 11 92%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 2 17%
Researcher 2 17%
Student > Ph. D. Student 2 17%
Student > Bachelor 1 8%
Student > Master 1 8%
Other 3 25%
Unknown 1 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 5 42%
Medicine and Dentistry 5 42%
Immunology and Microbiology 1 8%
Unknown 1 8%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 January 2009.
All research outputs
#816,114
of 3,631,167 outputs
Outputs from BMC Cancer
#296
of 1,786 outputs
Outputs of similar age
#24,988
of 95,757 outputs
Outputs of similar age from BMC Cancer
#11
of 61 outputs
Altmetric has tracked 3,631,167 research outputs across all sources so far. This one has received more attention than most of these and is in the 63rd percentile.
So far Altmetric has tracked 1,786 research outputs from this source. They receive a mean Attention Score of 2.6. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 95,757 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 61 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.