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Association of parental methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism in couples with unexplained recurrent pregnancy loss

Overview of attention for article published in BMC Research Notes, April 2018
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Title
Association of parental methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism in couples with unexplained recurrent pregnancy loss
Published in
BMC Research Notes, April 2018
DOI 10.1186/s13104-018-3321-x
Pubmed ID
Authors

Anil Kumar Sah, Nisha Shrestha, Pratikshya Joshi, Renu Lakha, Sweta Shrestha, Laxmi Sharma, Avinash Chandra, Neetu Singh, Yuvraj KC, Bhola Rijal

Abstract

The aim of this study was to identify the association of parental MTHFR C677T gene polymorphism in couples with and without RPL history. During the study, 21.4% (15/70) of Ala222Val polymorphism was observed among RPL couples while no polymorphism was seen among normal, healthy couples. Our study did not find any association between MTHFR C677T polymorphism and gender (p > 0.05), gestational period (p > 0.05), geographical region (p > 0.05) and menstrual history (p > 0.05). However, significant association was seen between MTHFR C677T polymorphism and number of losses (p < 0.05), concluding that the risk of the polymorphism increased with the increase in number of losses. Significant variation in the MTHFR C677T genotype with number of losses among RPL couples were seen but not with other study variables.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 52 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 9 17%
Unspecified 6 12%
Student > Postgraduate 5 10%
Student > Ph. D. Student 5 10%
Student > Bachelor 4 8%
Other 8 15%
Unknown 15 29%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 11 21%
Medicine and Dentistry 10 19%
Unspecified 6 12%
Agricultural and Biological Sciences 2 4%
Social Sciences 2 4%
Other 6 12%
Unknown 15 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 April 2018.
All research outputs
#14,851,325
of 23,041,514 outputs
Outputs from BMC Research Notes
#2,114
of 4,283 outputs
Outputs of similar age
#196,851
of 329,678 outputs
Outputs of similar age from BMC Research Notes
#44
of 98 outputs
Altmetric has tracked 23,041,514 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,283 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,678 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 98 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.