Title |
Relationship between treatment delay and final infarct size in STEMI patients treated with abciximab and primary PCI
|
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Published in |
BMC Cardiovascular Disorders, February 2012
|
DOI | 10.1186/1471-2261-12-9 |
Pubmed ID | |
Authors |
Tim Tödt, Eva Maret, Joakim Alfredsson, Magnus Janzon, Jan Engvall, Eva Swahn |
Abstract |
Studies on the impact of time to treatment on myocardial infarct size have yielded conflicting results. In this study of ST-Elevation Myocardial Infarction (STEMI) treated with primary percutaneous coronary intervention (PCI), we set out to investigate the relationship between the time from First Medical Contact (FMC) to the demonstration of an open infarct related artery (IRA) and final scar size.Between February 2006 and September 2007, 89 STEMI patients treated with primary PCI were studied with contrast enhanced magnetic resonance imaging (ceMRI) 4 to 8 weeks after the infarction. Spearman correlation was computed for health care delay time (defined as time from FMC to PCI) and myocardial injury. Multiple linear regression was used to determine covariates independently associated with infarct size. |
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