You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
Mendeley readers
Attention Score in Context
Title |
Prediction of cytochrome P450 isoform responsible for metabolizing a drug molecule
|
---|---|
Published in |
BMC Pharmacology, July 2010
|
DOI | 10.1186/1471-2210-10-8 |
Pubmed ID | |
Authors |
Nitish K Mishra, Sandhya Agarwal, Gajendra PS Raghava |
Abstract |
Different isoforms of Cytochrome P450 (CYP) metabolized different types of substrates (or drugs molecule) and make them soluble during biotransformation. Therefore, fate of any drug molecule depends on how they are treated or metabolized by CYP isoform. There is a need to develop models for predicting substrate specificity of major isoforms of P450, in order to understand whether a given drug will be metabolized or not. This paper describes an in-silico method for predicting the metabolizing capability of major isoforms (e.g. CYP 3A4, 2D6, 1A2, 2C9 and 2C19). |
Mendeley readers
The data shown below were compiled from readership statistics for 135 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 5 | 4% |
Brazil | 4 | 3% |
United Kingdom | 2 | 1% |
Bulgaria | 1 | <1% |
Unknown | 123 | 91% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 28 | 21% |
Student > Ph. D. Student | 25 | 19% |
Student > Master | 22 | 16% |
Student > Bachelor | 12 | 9% |
Professor | 8 | 6% |
Other | 22 | 16% |
Unknown | 18 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 30 | 22% |
Chemistry | 29 | 21% |
Biochemistry, Genetics and Molecular Biology | 13 | 10% |
Pharmacology, Toxicology and Pharmaceutical Science | 8 | 6% |
Medicine and Dentistry | 7 | 5% |
Other | 20 | 15% |
Unknown | 28 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 October 2010.
All research outputs
#7,454,951
of 22,790,780 outputs
Outputs from BMC Pharmacology
#26
of 63 outputs
Outputs of similar age
#33,950
of 95,152 outputs
Outputs of similar age from BMC Pharmacology
#2
of 2 outputs
Altmetric has tracked 22,790,780 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 63 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 95,152 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one.