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Mendeley readers
Attention Score in Context
| Title |
A “reverse pharmacology” approach for developing an anti-malarial phytomedicine
|
|---|---|
| Published in |
Malaria Journal, March 2011
|
| DOI | 10.1186/1475-2875-10-s1-s8 |
| Pubmed ID | |
| Authors |
Merlin L Willcox, Bertrand Graz, Jacques Falquet, Chiaka Diakite, Sergio Giani, Drissa Diallo |
| Abstract |
A "reverse pharmacology" approach to developing an anti-malarial phytomedicine was designed and implemented in Mali, resulting in a new standardized herbal anti-malarial after six years of research. The first step was to select a remedy for development, through a retrospective treatment-outcome study. The second step was a dose-escalating clinical trial that showed a dose-response phenomenon and helped select the safest and most efficacious dose. The third step was a randomized controlled trial to compare the phytomedicine to the standard first-line treatment. The last step was to identify active compounds which can be used as markers for standardization and quality control. This example of "reverse pharmacology" shows that a standardized phytomedicine can be developed faster and more cheaply than conventional drugs. Even if both approaches are not fully comparable, their efficiency in terms of public health and their complementarity should be thoroughly considered. |
Mendeley readers
The data shown below were compiled from readership statistics for 149 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | <1% |
| Uganda | 1 | <1% |
| Indonesia | 1 | <1% |
| United Kingdom | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 144 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 29 | 19% |
| Researcher | 19 | 13% |
| Student > Master | 17 | 11% |
| Student > Postgraduate | 10 | 7% |
| Other | 9 | 6% |
| Other | 35 | 23% |
| Unknown | 30 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 29 | 19% |
| Medicine and Dentistry | 21 | 14% |
| Chemistry | 18 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 16 | 11% |
| Social Sciences | 7 | 5% |
| Other | 19 | 13% |
| Unknown | 39 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 September 2020.
All research outputs
#7,454,951
of 22,790,780 outputs
Outputs from Malaria Journal
#2,448
of 5,561 outputs
Outputs of similar age
#39,155
of 108,141 outputs
Outputs of similar age from Malaria Journal
#18
of 42 outputs
Altmetric has tracked 22,790,780 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,561 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one is in the 47th percentile – i.e., 47% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 108,141 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 42 others from the same source and published within six weeks on either side of this one. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.