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Comparative profiling of the transcriptional response to iron restriction in six serotypes of Actinobacillus pleuropneumoniae with different virulence potential

Overview of attention for article published in BMC Genomics, January 2010
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  • Good Attention Score compared to outputs of the same age (70th percentile)
  • Good Attention Score compared to outputs of the same age and source (65th percentile)

Mentioned by

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1 Wikipedia page

Citations

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17 Dimensions

Readers on

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40 Mendeley
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Title
Comparative profiling of the transcriptional response to iron restriction in six serotypes of Actinobacillus pleuropneumoniae with different virulence potential
Published in
BMC Genomics, January 2010
DOI 10.1186/1471-2164-11-698
Pubmed ID
Authors

Kirstine Klitgaard, Carsten Friis, Øystein Angen, Mette Boye

Abstract

Comparative analysis of gene expression among serotypes within a species can provide valuable information on important differences between related genomes. For the pig lung pathogen Actinobacillus pleuropneumoniae, 15 serotypes with a considerable variation in virulence potential and immunogenicity have been identified. This serotypic diversity can only partly be explained by amount of capsule and differences in the RTX toxin genes in their genomes. Iron acquisition in vivo is an important bacterial function and in pathogenic bacteria, iron-limitation is often a signal for the induction of virulence genes. We used a pan-genomic microarray to study the transcriptional response to iron restriction in vitro in six serotypes of A. pleuropneumoniae (1, 2, 3, 5b, 6, and 7), representing at least two levels of virulence.

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
United States 1 3%
Brazil 1 3%
Unknown 37 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 23%
Student > Bachelor 7 18%
Researcher 7 18%
Student > Doctoral Student 3 8%
Student > Master 3 8%
Other 7 18%
Unknown 4 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 19 48%
Biochemistry, Genetics and Molecular Biology 6 15%
Environmental Science 2 5%
Medicine and Dentistry 2 5%
Nursing and Health Professions 1 3%
Other 4 10%
Unknown 6 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 April 2013.
All research outputs
#982,983
of 4,351,319 outputs
Outputs from BMC Genomics
#1,047
of 3,945 outputs
Outputs of similar age
#43,378
of 152,631 outputs
Outputs of similar age from BMC Genomics
#67
of 204 outputs
Altmetric has tracked 4,351,319 research outputs across all sources so far. This one has received more attention than most of these and is in the 64th percentile.
So far Altmetric has tracked 3,945 research outputs from this source. They receive a mean Attention Score of 3.3. This one has gotten more attention than average, scoring higher than 67% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 152,631 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 204 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.