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Identification of genes for small non-coding RNAs that belong to the regulon of the two-component regulatory system CiaRH in Streptococcus

Overview of attention for article published in BMC Genomics, November 2010
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  • Good Attention Score compared to outputs of the same age (68th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (63rd percentile)

Mentioned by

wikipedia
1 Wikipedia page

Citations

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35 Dimensions

Readers on

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36 Mendeley
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Title
Identification of genes for small non-coding RNAs that belong to the regulon of the two-component regulatory system CiaRH in Streptococcus
Published in
BMC Genomics, November 2010
DOI 10.1186/1471-2164-11-661
Pubmed ID
Authors

Patrick Marx, Michael Nuhn, Martá Kovács, Regine Hakenbeck, Reinhold Brückner

Abstract

Post-transcriptional regulation by small RNAs (sRNAs) in bacteria is now recognized as a wide-spread regulatory mechanism modulating a variety of physiological responses including virulence. In Streptococcus pneumoniae, an important human pathogen, the first sRNAs to be described were found in the regulon of the CiaRH two-component regulatory system. Five of these sRNAs were detected and designated csRNAs for cia-dependent small RNAs. CiaRH pleiotropically affects β-lactam resistance, autolysis, virulence, and competence development by yet to be defined molecular mechanisms. Since CiaRH is highly conserved among streptococci, it is of interest to determine if csRNAs are also included in the CiaRH regulon in this group of organisms consisting of commensal as well as pathogenic species. Knowledge on the participation of csRNAs in CiaRH-dependent regulatory events will be the key to define the physiological role of this important control system.

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 36 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 33%
Professor > Associate Professor 5 14%
Researcher 5 14%
Student > Bachelor 3 8%
Other 1 3%
Other 4 11%
Unknown 6 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 19 53%
Biochemistry, Genetics and Molecular Biology 6 17%
Immunology and Microbiology 2 6%
Arts and Humanities 1 3%
Medicine and Dentistry 1 3%
Other 0 0%
Unknown 7 19%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 December 2012.
All research outputs
#916,767
of 3,988,878 outputs
Outputs from BMC Genomics
#1,007
of 3,633 outputs
Outputs of similar age
#40,551
of 132,941 outputs
Outputs of similar age from BMC Genomics
#69
of 200 outputs
Altmetric has tracked 3,988,878 research outputs across all sources so far. This one has received more attention than most of these and is in the 63rd percentile.
So far Altmetric has tracked 3,633 research outputs from this source. They receive a mean Attention Score of 3.5. This one has gotten more attention than average, scoring higher than 66% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 132,941 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.
We're also able to compare this research output to 200 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.