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Toll-like receptors in lupus nephritis

Overview of attention for article published in Journal of Biomedical Science, April 2018
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (78th percentile)

Mentioned by

twitter
6 tweeters
patent
1 patent
q&a
1 Q&A thread

Citations

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45 Dimensions

Readers on

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52 Mendeley
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Title
Toll-like receptors in lupus nephritis
Published in
Journal of Biomedical Science, April 2018
DOI 10.1186/s12929-018-0436-2
Pubmed ID
Authors

Satish Kumar Devarapu, Hans-Joachim Anders

Abstract

The pathogenesis of systemic autoimmune diseases such as systemic lupus erythematosus (SLE) is based on the loss of self-tolerance against ubiquitous autoantigens involving all mechanisms of adaptive immunity. However, data accumulating over the last decade imply an important role also for numerous elements of innate immunity, namely the Toll-like receptors in the pathogenesis of SLE. Here we discuss their role in the most common organ complication of SLE, i.e. lupus nephritis. We summarize experimental and clinical data on the expression and functional contribution of the Toll-like receptors in immune complex glomerulonephritis, and intrarenal inflammation. Based on these discoveries Toll-like receptors are evolving as therapeutic targets for the treatment of SLE and lupus nephritis.

Twitter Demographics

The data shown below were collected from the profiles of 6 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 52 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 15%
Researcher 7 13%
Other 6 12%
Student > Ph. D. Student 6 12%
Student > Postgraduate 4 8%
Other 9 17%
Unknown 12 23%
Readers by discipline Count As %
Medicine and Dentistry 15 29%
Biochemistry, Genetics and Molecular Biology 7 13%
Immunology and Microbiology 6 12%
Agricultural and Biological Sciences 4 8%
Pharmacology, Toxicology and Pharmaceutical Science 4 8%
Other 2 4%
Unknown 14 27%

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 December 2021.
All research outputs
#3,264,964
of 21,321,610 outputs
Outputs from Journal of Biomedical Science
#125
of 923 outputs
Outputs of similar age
#64,211
of 298,767 outputs
Outputs of similar age from Journal of Biomedical Science
#1
of 1 outputs
Altmetric has tracked 21,321,610 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 923 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.9. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 298,767 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 78% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them