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Modelling the return on investment of preventively vaccinating healthcare workers against pertussis

Overview of attention for article published in BMC Infectious Diseases, February 2015
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Title
Modelling the return on investment of preventively vaccinating healthcare workers against pertussis
Published in
BMC Infectious Diseases, February 2015
DOI 10.1186/s12879-015-0800-8
Pubmed ID
Authors

Luqman Tariq, Marie-Josée J Mangen, Anke Hövels, Gerard Frijstein, Hero de Boer

Abstract

Healthcare workers (HCWs) are at particular risk of acquiring pertussis and transmitting the infection to high-risk susceptible patients and colleagues. In this paper, the return on investment (ROI) of preventively vaccinating HCWs against pertussis to prevent nosocomial pertussis outbreaks is estimated using a hospital ward perspective, presuming an outbreak occurs once in 10 years. Data on the pertussis outbreak on the neonatology ward in 2004 in the Academic Medical Center Amsterdam (The Netherlands) was used to calculate control costs and other outbreak related costs. The study population was: neonatology ward staff members (n = 133), parents (n = 40), neonates (n = 20), and newborns transferred to other hospitals (n = 23). ROI is presented as the amount of Euros saved in averting outbreaks by investing one Euro in preventively vaccinating HCWs. Sensitivity analysis was performed to study the robustness of the ROI. Results are presented at 2012 price level. Total nosocomial pertussis outbreak costs were €48,682. Direct control costs (i.e. antibiotic therapy, laboratory investigation and outbreak management control) were €11,464. Other outbreak related costs (i.e. sick leave of HCWs; restrictions on the neonatology ward, savings due to reduced working force required) accounted for €37,218. Vaccination costs were estimated at €12,208. The ROI of preventively vaccinating HCWs against pertussis was 1:4, meaning 4 Euros could be saved by every Euro invested in vaccinating HCWs to avert outbreaks. ROI was sensitive to a lower vaccine price, considering direct control costs only, average length of stay of neonates on the neonatology ward, length of patient uptake restrictions, assuming no reduced work force due to ward closer and presuming more than one outbreak to occur in 10 years' time. From a hospital ward perspective, preventive vaccination of HCWs against pertussis to prevent nosocomial pertussis outbreaks results in a positive ROI, presuming an outbreak occurs once in 10 years.

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Mendeley readers

Mendeley readers

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Geographical breakdown

Country Count As %
United Kingdom 1 2%
Unknown 49 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 22%
Student > Master 11 22%
Student > Ph. D. Student 5 10%
Student > Doctoral Student 4 8%
Student > Postgraduate 4 8%
Other 5 10%
Unknown 10 20%
Readers by discipline Count As %
Medicine and Dentistry 8 16%
Nursing and Health Professions 7 14%
Economics, Econometrics and Finance 7 14%
Pharmacology, Toxicology and Pharmaceutical Science 6 12%
Social Sciences 3 6%
Other 6 12%
Unknown 13 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 February 2015.
All research outputs
#20,262,276
of 22,792,160 outputs
Outputs from BMC Infectious Diseases
#6,465
of 7,674 outputs
Outputs of similar age
#214,945
of 255,121 outputs
Outputs of similar age from BMC Infectious Diseases
#150
of 159 outputs
Altmetric has tracked 22,792,160 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,674 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.6. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 159 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.