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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Inhibition of iNOS as a novel effective targeted therapy against triple-negative breast cancer
|
|---|---|
| Published in |
Breast Cancer Research, February 2015
|
| DOI | 10.1186/s13058-015-0527-x |
| Pubmed ID | |
| Authors |
Sergio Granados-Principal, Yi Liu, Maria L Guevara, Elvin Blanco, Dong Soon Choi, Wei Qian, Tejal Patel, Angel A Rodriguez, Joseph Cusimano, Heidi L Weiss, Hong Zhao, Melissa D Landis, Bhuvanesh Dave, Steven S Gross, Jenny C Chang |
| Abstract |
Triple negative breast cancer (TNBC) is an aggressive form of breast cancer with no effective targeted therapy. Inducible nitric oxide synthase (iNOS) is associated with poor survival in breast cancer patients by increasing tumor aggressiveness. This work aimed to investigate the potential of iNOS inhibitors as a targeted therapy for TNBC. We hypothesized that inhibition of endogenous iNOS would decrease TNBC aggressiveness by reducing tumor initiation and metastasis through modulation of epithelial-mesenchymal transition (EMT)-inducing factors. |
X Demographics
The data shown below were collected from the profiles of 12 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 17% |
| Netherlands | 2 | 17% |
| India | 1 | 8% |
| United Kingdom | 1 | 8% |
| Unknown | 6 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 9 | 75% |
| Science communicators (journalists, bloggers, editors) | 2 | 17% |
| Scientists | 1 | 8% |
Mendeley readers
The data shown below were compiled from readership statistics for 190 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | <1% |
| Mexico | 1 | <1% |
| Belgium | 1 | <1% |
| Denmark | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 185 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 31 | 16% |
| Student > Bachelor | 30 | 16% |
| Researcher | 23 | 12% |
| Student > Master | 21 | 11% |
| Student > Doctoral Student | 9 | 5% |
| Other | 28 | 15% |
| Unknown | 48 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 46 | 24% |
| Medicine and Dentistry | 24 | 13% |
| Agricultural and Biological Sciences | 23 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 13 | 7% |
| Chemistry | 9 | 5% |
| Other | 20 | 11% |
| Unknown | 55 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 43. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 June 2022.
All research outputs
#844,460
of 23,342,092 outputs
Outputs from Breast Cancer Research
#71
of 1,923 outputs
Outputs of similar age
#11,276
of 256,215 outputs
Outputs of similar age from Breast Cancer Research
#3
of 51 outputs
Altmetric has tracked 23,342,092 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,923 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 256,215 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 51 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.