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The influence of heterocyclic compound-PAMAM dendrimer complexes on evoked electrical responses in slices of hypoxic brain tissue

Overview of attention for article published in Cellular & Molecular Biology Letters, April 2014
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Title
The influence of heterocyclic compound-PAMAM dendrimer complexes on evoked electrical responses in slices of hypoxic brain tissue
Published in
Cellular & Molecular Biology Letters, April 2014
DOI 10.2478/s11658-014-0193-5
Pubmed ID
Authors

Vladimir Potkin, Dzmitry Shcharbin, Andrey Denisov, Svetlana Paschkevich, Maria Bryszewska, Sergey Petkevich, Alexey Kletskov, Dmitri Lapotko, Vladimir Kazbanov, Tatiana Gurinovich, Vladimir Kulchitsky

Abstract

We used complexes between a fourth generation polyamidoamine (PAMAM) dendrimer and one of two heterocyclic compounds - 1-(6-hydroxyhexyl)-3-(5-phenyl-isoxazole-3-yl)-urea or 5-phenyl-isoxazole-3-carboxylic acid - to reduce oxygen consumption in transverse slices of the hippocampus taken from 4-week old male rats. In vitro electrophysiological experiments revealed that the inhibitory effect of the hypoxic state on the evoked responses was enhanced in the presence of the complexes. The data were analyzed in terms of the potential antitumor effects of these complexes.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 12 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 42%
Student > Master 2 17%
Other 1 8%
Student > Ph. D. Student 1 8%
Unknown 3 25%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 3 25%
Neuroscience 2 17%
Physics and Astronomy 1 8%
Medicine and Dentistry 1 8%
Chemistry 1 8%
Other 0 0%
Unknown 4 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 February 2015.
All research outputs
#22,759,452
of 25,374,647 outputs
Outputs from Cellular & Molecular Biology Letters
#463
of 606 outputs
Outputs of similar age
#209,562
of 241,719 outputs
Outputs of similar age from Cellular & Molecular Biology Letters
#4
of 4 outputs
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So far Altmetric has tracked 606 research outputs from this source. They receive a mean Attention Score of 2.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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