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Clonal dissemination of linezolid-resistant Staphylococcus capitis with G2603T mutation in domain V of the 23S rRNA and the cfr gene at a tertiary care hospital in China

Overview of attention for article published in BMC Infectious Diseases, February 2015
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Title
Clonal dissemination of linezolid-resistant Staphylococcus capitis with G2603T mutation in domain V of the 23S rRNA and the cfr gene at a tertiary care hospital in China
Published in
BMC Infectious Diseases, February 2015
DOI 10.1186/s12879-015-0841-z
Pubmed ID
Authors

Wanqing Zhou, Dongmei Niu, Xiaoli Cao, Mingzhe Ning, Zhifeng Zhang, Han Shen, Kui Zhang

Abstract

The present study aims to investigate the potential mechanism of linezolid-resistant Staphylococcus capitis (LRSC) isolates collected from our hospital. The susceptibilities of 5 Staphylococcus capitis isolates displaying resistance towards linezolid were determined by E-test. Polymerase chain reactions (PCRs) and DNA sequencing were used to investigate the potential molecular mechanism. Clonal relatedness between these strains was analyzed by pulsed-field gel electrophoresis (PFGE). The MICs of linezolid on these 5 isolates were >256 μg/mL. The G2603T mutation was observed in the domain V of the 23S rRNA with cfr gene being also widely detected among these 5 strains. PFGE analysis displayed close genetic relatedness between these linezolid-resistant isolates. The emergence of LRSC isolates carrying G2603T mutation in the domain V of the 23S rRNA and harboring cfr gene in our hospital may pose a potential challenge to the public health.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 32 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 25%
Student > Ph. D. Student 5 16%
Researcher 3 9%
Other 2 6%
Student > Bachelor 2 6%
Other 4 13%
Unknown 8 25%
Readers by discipline Count As %
Medicine and Dentistry 7 22%
Immunology and Microbiology 5 16%
Biochemistry, Genetics and Molecular Biology 3 9%
Agricultural and Biological Sciences 3 9%
Environmental Science 1 3%
Other 2 6%
Unknown 11 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 February 2015.
All research outputs
#18,401,956
of 22,793,427 outputs
Outputs from BMC Infectious Diseases
#5,596
of 7,674 outputs
Outputs of similar age
#185,612
of 255,469 outputs
Outputs of similar age from BMC Infectious Diseases
#109
of 158 outputs
Altmetric has tracked 22,793,427 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,674 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.6. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 255,469 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 158 others from the same source and published within six weeks on either side of this one. This one is in the 5th percentile – i.e., 5% of its contemporaries scored the same or lower than it.