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Oral consumption of α-linolenic acid increases serum BDNF levels in healthy adult humans

Overview of attention for article published in Nutrition Journal, February 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)

Mentioned by

news
2 news outlets
twitter
4 tweeters
facebook
3 Facebook pages
reddit
2 Redditors

Citations

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18 Dimensions

Readers on

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69 Mendeley
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Title
Oral consumption of α-linolenic acid increases serum BDNF levels in healthy adult humans
Published in
Nutrition Journal, February 2015
DOI 10.1186/s12937-015-0012-5
Pubmed ID
Authors

Mahmoudreza Hadjighassem, Behnam Kamalidehghan, Nima Shekarriz, Argavan Baseerat, Nima Molavi, Masoud Mehrpour, Mohammad Taghi Joghataei, Mahdi Tondar, Fatemeh Ahmadipour, Goh Yong Meng

Abstract

Dietary omega-6 and omega-3 fatty acids have remarkable impacts on the levels of DHA in the brain and retina. Low levels of DHA in plasma and blood hamper visual and neural development in children and cause dementia and cognitive decline in adults. The level of brain-derived neurotrophic factors (BDNF) changes with dietary omega-3 fatty acid intake. BDNF is known for its effects on promoting neurogenesis and neuronal survival. In this study, we examined the effect of the oral consumption of α-Linolenic acid (ALA) on blood levels of BDNF and Malondialdehyde (MDA) in healthy adult humans. 30 healthy volunteers, 15 men and 15 women, were selected randomly. Each individual served as his or her own control. Before consuming the Flaxseed oil capsules, 5cc blood from each individual was sampled in order to measure the plasma levels of BDNF and MDA as baseline controls. During the experiment, each individual was given 3 oral capsules of flaxseed oil, containing 500mg of alpha linolenic acid, daily for one week. Then, plasma levels of BDNF and MDA were tested. The plasma levels of BDNF and MDA significantly (P < 0.05) increased in individuals who received the oral capsules of ALA. Plasma levels of BDNF increased more in the women in comparison with the men. ALA treatment could be a feasible approach to reduce size of infarcts in stroke patients. Thus, ALA could be used in adjunction with routine stroke therapies to minimize brain lesions caused by stroke.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 69 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 1%
Unknown 68 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 13%
Student > Bachelor 9 13%
Other 8 12%
Researcher 8 12%
Student > Master 7 10%
Other 10 14%
Unknown 18 26%
Readers by discipline Count As %
Medicine and Dentistry 14 20%
Biochemistry, Genetics and Molecular Biology 9 13%
Psychology 6 9%
Agricultural and Biological Sciences 6 9%
Nursing and Health Professions 6 9%
Other 11 16%
Unknown 17 25%

Attention Score in Context

This research output has an Altmetric Attention Score of 24. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 June 2021.
All research outputs
#1,011,181
of 17,979,785 outputs
Outputs from Nutrition Journal
#295
of 1,315 outputs
Outputs of similar age
#15,620
of 223,194 outputs
Outputs of similar age from Nutrition Journal
#1
of 1 outputs
Altmetric has tracked 17,979,785 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,315 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 30.3. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 223,194 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them