Title |
Association of chronic diabetes and hypertension in sural nerve morphometry: an experimental study
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Published in |
Diabetology & Metabolic Syndrome, February 2015
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DOI | 10.1186/s13098-015-0005-8 |
Pubmed ID | |
Authors |
Luciana Sayuri Sanada, Marcelo Rodrigo Tavares, Karina Laurenti Sato, Renata da Silva Ferreira, Milena Cardoso Maia Neubern, Jaci Ayrton Castania, Helio Cesar Salgado, Valéria Paula Sassoli Fazan |
Abstract |
Prospective studies have shown incidence rates of hypertension in diabetes mellitus to be three times that of subjects without diabetes mellitus. The reverse also applies, with the incidence of diabetes two to three times higher in patients with hypertension. Despite this common clinical association, the contribution of each isolated entity in the development of a neuropathy is still not well understood. The aims of the present study were to investigate the presence of peripheral neuropathy in spontaneously hypertensive rats (SHR) and SHR with chronically induced diabetes, using a morphological and morphometric study of the sural nerves. |
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