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Vitamin B12 insufficiency induces cholesterol biosynthesis by limiting s-adenosylmethionine and modulating the methylation of SREBF1 and LDLR genes

Overview of attention for article published in Clinical Epigenetics, February 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)

Mentioned by

twitter
20 tweeters
facebook
1 Facebook page

Citations

dimensions_citation
66 Dimensions

Readers on

mendeley
127 Mendeley
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Title
Vitamin B12 insufficiency induces cholesterol biosynthesis by limiting s-adenosylmethionine and modulating the methylation of SREBF1 and LDLR genes
Published in
Clinical Epigenetics, February 2015
DOI 10.1186/s13148-015-0046-8
Pubmed ID
Authors

Antonysunil Adaikalakoteswari, Sarah Finer, Philip D Voyias, Ciara M McCarthy, Manu Vatish, Jonathan Moore, Melissa Smart-Halajko, Nahla Bawazeer, Nasser M Al-Daghri, Philip G McTernan, Sudhesh Kumar, Graham A Hitman, Ponnusamy Saravanan, Gyanendra Tripathi

Abstract

The dietary supply of methyl donors such as folate, vitamin B12, betaine, methionine, and choline is essential for normal growth, development, and physiological functions through the life course. Both human and animal studies have shown that vitamin B12 deficiency is associated with altered lipid profile and play an important role in the prediction of metabolic risk, however, as of yet, no direct mechanism has been investigated to confirm this.

Twitter Demographics

The data shown below were collected from the profiles of 20 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 127 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
United States 1 <1%
Netherlands 1 <1%
Brazil 1 <1%
Unknown 123 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 27 21%
Student > Master 17 13%
Researcher 15 12%
Student > Bachelor 12 9%
Professor > Associate Professor 10 8%
Other 28 22%
Unknown 18 14%
Readers by discipline Count As %
Medicine and Dentistry 35 28%
Biochemistry, Genetics and Molecular Biology 29 23%
Agricultural and Biological Sciences 19 15%
Nursing and Health Professions 8 6%
Neuroscience 3 2%
Other 9 7%
Unknown 24 19%

Attention Score in Context

This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 April 2022.
All research outputs
#1,978,505
of 21,544,335 outputs
Outputs from Clinical Epigenetics
#116
of 1,165 outputs
Outputs of similar age
#25,749
of 230,401 outputs
Outputs of similar age from Clinical Epigenetics
#1
of 1 outputs
Altmetric has tracked 21,544,335 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,165 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 230,401 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them