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Vitamin B12 insufficiency induces cholesterol biosynthesis by limiting s-adenosylmethionine and modulating the methylation of SREBF1 and LDLR genes

Overview of attention for article published in Clinical Epigenetics, February 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (93rd percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

news
1 news outlet
twitter
31 X users
facebook
1 Facebook page

Citations

dimensions_citation
86 Dimensions

Readers on

mendeley
152 Mendeley
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Title
Vitamin B12 insufficiency induces cholesterol biosynthesis by limiting s-adenosylmethionine and modulating the methylation of SREBF1 and LDLR genes
Published in
Clinical Epigenetics, February 2015
DOI 10.1186/s13148-015-0046-8
Pubmed ID
Authors

Antonysunil Adaikalakoteswari, Sarah Finer, Philip D Voyias, Ciara M McCarthy, Manu Vatish, Jonathan Moore, Melissa Smart-Halajko, Nahla Bawazeer, Nasser M Al-Daghri, Philip G McTernan, Sudhesh Kumar, Graham A Hitman, Ponnusamy Saravanan, Gyanendra Tripathi

Abstract

The dietary supply of methyl donors such as folate, vitamin B12, betaine, methionine, and choline is essential for normal growth, development, and physiological functions through the life course. Both human and animal studies have shown that vitamin B12 deficiency is associated with altered lipid profile and play an important role in the prediction of metabolic risk, however, as of yet, no direct mechanism has been investigated to confirm this.

X Demographics

X Demographics

The data shown below were collected from the profiles of 31 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 152 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
United States 1 <1%
Netherlands 1 <1%
Brazil 1 <1%
Unknown 148 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 28 18%
Student > Master 22 14%
Researcher 17 11%
Student > Bachelor 12 8%
Professor > Associate Professor 10 7%
Other 30 20%
Unknown 33 22%
Readers by discipline Count As %
Medicine and Dentistry 36 24%
Biochemistry, Genetics and Molecular Biology 32 21%
Agricultural and Biological Sciences 20 13%
Nursing and Health Professions 11 7%
Neuroscience 3 2%
Other 11 7%
Unknown 39 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 29. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 November 2023.
All research outputs
#1,357,106
of 25,362,278 outputs
Outputs from Clinical Epigenetics
#70
of 1,436 outputs
Outputs of similar age
#16,768
of 270,044 outputs
Outputs of similar age from Clinical Epigenetics
#4
of 42 outputs
Altmetric has tracked 25,362,278 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,436 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 270,044 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 42 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.