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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The role of epigenetics in personalized medicine: challenges and opportunities
|
|---|---|
| Published in |
BMC Medical Genomics, January 2015
|
| DOI | 10.1186/1755-8794-8-s1-s5 |
| Pubmed ID | |
| Authors |
Mahmood Rasool, Arif Malik, Muhammad Imran Naseer, Abdul Manan, Shakeel Ahmed Ansari, Irshad Begum, Mahmood Husain Qazi, Peter Natesan Pushparaj, Adel M Abuzenadah, Mohammed Hussein Al-Qahtani, Mohammad Amjad Kamal, Siew Hua Gan |
| Abstract |
Epigenetic alterations are considered to be very influential in both the normal and disease states of an organism. These alterations include methylation, acetylation, phosphorylation, and ubiquitylation of DNA and histone proteins (nucleosomes) as well as chromatin remodeling. Many diseases, such as cancers and neurodegenerative disorders, are often associated with epigenetic alterations. DNA methylation is one important modification that leads to disease. Standard therapies are given to patients; however, few patients respond to these drugs, because of various molecular alterations in their cells, which may be partially due to genetic heterogeneity and epigenetic alterations. To realize the promise of personalized medicine, both genetic and epigenetic diagnostic testing will be required. This review will discuss the advances that have been made as well as the challenges for the future. |
X Demographics
The data shown below were collected from the profiles of 15 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 27% |
| Guatemala | 1 | 7% |
| Norway | 1 | 7% |
| Italy | 1 | 7% |
| United Kingdom | 1 | 7% |
| France | 1 | 7% |
| Canada | 1 | 7% |
| Unknown | 5 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 11 | 73% |
| Scientists | 2 | 13% |
| Practitioners (doctors, other healthcare professionals) | 2 | 13% |
Mendeley readers
The data shown below were compiled from readership statistics for 204 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Philippines | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 202 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 35 | 17% |
| Student > Master | 31 | 15% |
| Researcher | 27 | 13% |
| Student > Ph. D. Student | 21 | 10% |
| Other | 11 | 5% |
| Other | 31 | 15% |
| Unknown | 48 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 40 | 20% |
| Agricultural and Biological Sciences | 29 | 14% |
| Medicine and Dentistry | 24 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 12 | 6% |
| Immunology and Microbiology | 7 | 3% |
| Other | 37 | 18% |
| Unknown | 55 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 32. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 January 2024.
All research outputs
#1,210,009
of 25,139,853 outputs
Outputs from BMC Medical Genomics
#23
of 1,385 outputs
Outputs of similar age
#17,656
of 392,717 outputs
Outputs of similar age from BMC Medical Genomics
#1
of 38 outputs
Altmetric has tracked 25,139,853 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,385 research outputs from this source. They receive a mean Attention Score of 4.6. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 392,717 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 38 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.