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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Mitochondrial and sex steroid hormone crosstalk during aging
|
|---|---|
| Published in |
Longevity & Healthspan, February 2014
|
| DOI | 10.1186/2046-2395-3-2 |
| Pubmed ID | |
| Authors |
Michael C Velarde |
| Abstract |
Decline in circulating sex steroid hormones accompanies several age-associated pathologies which may influence human healthspan. Mitochondria play important roles in biosynthesis of sex steroid hormones, and these hormones can also regulate mitochondrial function. Understanding the cross talk between mitochondria and sex steroid hormones may provide insights into the pathologies associated with aging. The aim of this review is to summarize the current knowledge regarding the interplay between mitochondria and sex steroid hormones during the aging process. The review describes the effect of mitochondria on sex steroid hormone production in the gonads, and then enumerates the contribution of sex steroid hormones on mitochondrial function in hormone responsive cells. Decline in sex steroid hormones and accumulation of mitochondrial damage may create a positive feedback loop that contributes to the progressive degeneration in tissue function during aging. The review further speculates whether regulation between mitochondrial function and sex steroid hormone action can potentially influence healthspan. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| New Zealand | 1 | 25% |
| United Kingdom | 1 | 25% |
| Unknown | 2 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Scientists | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 112 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Unknown | 111 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 23 | 21% |
| Researcher | 21 | 19% |
| Student > Master | 12 | 11% |
| Student > Bachelor | 10 | 9% |
| Student > Doctoral Student | 9 | 8% |
| Other | 21 | 19% |
| Unknown | 16 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 24 | 21% |
| Medicine and Dentistry | 23 | 21% |
| Biochemistry, Genetics and Molecular Biology | 23 | 21% |
| Neuroscience | 7 | 6% |
| Nursing and Health Professions | 4 | 4% |
| Other | 10 | 9% |
| Unknown | 21 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 July 2020.
All research outputs
#7,652,206
of 23,298,349 outputs
Outputs from Longevity & Healthspan
#22
of 26 outputs
Outputs of similar age
#94,081
of 309,876 outputs
Outputs of similar age from Longevity & Healthspan
#2
of 3 outputs
Altmetric has tracked 23,298,349 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 26 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.2. This one scored the same or higher as 4 of them.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 309,876 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.