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Measuring phenotype-phenotype similarity through the interactome

Overview of attention for article published in BMC Bioinformatics, April 2018
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Title
Measuring phenotype-phenotype similarity through the interactome
Published in
BMC Bioinformatics, April 2018
DOI 10.1186/s12859-018-2102-9
Pubmed ID
Authors

Jiajie Peng, Weiwei Hui, Xuequn Shang

Abstract

Recently, measuring phenotype similarity began to play an important role in disease diagnosis. Researchers have begun to pay attention to develop phenotype similarity measurement. However, existing methods ignore the interactions between phenotype-associated proteins, which may lead to inaccurate phenotype similarity. We proposed a network-based method PhenoNet to calculate the similarity between phenotypes. We localized phenotypes in the network and calculated the similarity between phenotype-associated modules by modeling both the inter- and intra-similarity. PhenoNet was evaluated on two independent evaluation datasets: gene ontology and gene expression data. The result shows that PhenoNet performs better than the state-of-art methods on all evaluation tests.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 25 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 16%
Student > Postgraduate 3 12%
Professor 2 8%
Student > Doctoral Student 2 8%
Researcher 2 8%
Other 1 4%
Unknown 11 44%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 5 20%
Computer Science 4 16%
Medicine and Dentistry 2 8%
Agricultural and Biological Sciences 2 8%
Mathematics 1 4%
Other 0 0%
Unknown 11 44%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 April 2018.
All research outputs
#20,481,952
of 23,043,346 outputs
Outputs from BMC Bioinformatics
#6,893
of 7,318 outputs
Outputs of similar age
#290,344
of 329,173 outputs
Outputs of similar age from BMC Bioinformatics
#90
of 106 outputs
Altmetric has tracked 23,043,346 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,318 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 106 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.