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OX40 ligand expressed in glioblastoma modulates adaptive immunity depending on the microenvironment: a clue for successful immunotherapy

Overview of attention for article published in Molecular Cancer, February 2015
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  • Above-average Attention Score compared to outputs of the same age and source (55th percentile)

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3 X users

Citations

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39 Dimensions

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94 Mendeley
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Title
OX40 ligand expressed in glioblastoma modulates adaptive immunity depending on the microenvironment: a clue for successful immunotherapy
Published in
Molecular Cancer, February 2015
DOI 10.1186/s12943-015-0307-3
Pubmed ID
Authors

Ichiyo Shibahara, Ryuta Saito, Rong Zhang, Masashi Chonan, Takuhiro Shoji, Masayuki Kanamori, Yukihiko Sonoda, Toshihiro Kumabe, Masahiko Kanehira, Toshiaki Kikuchi, Takanori So, Takashi Watanabe, Hiroaki Takahashi, Erina Iwabuchi, Yuetsu Tanaka, Yukiko Shibahara, Hironobu Sasano, Naoto Ishii, Teiji Tominaga

Abstract

Glioblastoma is the most malignant human brain tumor and has a dismal prognosis; however, some patients show long-term survival. The interaction between the costimulatory molecule OX40 and its ligand OX40L generates key signals for T-cell activation. The augmentation of this interaction enhances antitumor immunity. In this present study, we explored whether OX40 signaling is responsible for antitumor adaptive immunity against glioblastoma and also established therapeutic antiglioma vaccination therapy.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 94 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Korea, Republic of 1 1%
Brazil 1 1%
Unknown 92 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 24 26%
Researcher 21 22%
Student > Doctoral Student 10 11%
Student > Bachelor 8 9%
Student > Master 5 5%
Other 9 10%
Unknown 17 18%
Readers by discipline Count As %
Medicine and Dentistry 25 27%
Agricultural and Biological Sciences 14 15%
Biochemistry, Genetics and Molecular Biology 11 12%
Immunology and Microbiology 11 12%
Neuroscience 4 4%
Other 8 9%
Unknown 21 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 January 2016.
All research outputs
#14,718,998
of 23,577,654 outputs
Outputs from Molecular Cancer
#944
of 1,782 outputs
Outputs of similar age
#209,767
of 389,014 outputs
Outputs of similar age from Molecular Cancer
#22
of 56 outputs
Altmetric has tracked 23,577,654 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,782 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 389,014 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 56 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.