Title |
Differential Evolution approach to detect recent admixture
|
---|---|
Published in |
BMC Genomics, June 2015
|
DOI | 10.1186/1471-2164-16-s8-s9 |
Pubmed ID | |
Authors |
Konstantin Kozlov, Dmitri Chebotarev, Mehedi Hassan, Martin Triska, Petr Triska, Pavel Flegontov, Tatiana V Tatarinova |
Abstract |
The genetic structure of human populations is extraordinarily complex and of fundamental importance to studies of anthropology, evolution, and medicine. As increasingly many individuals are of mixed origin, there is an unmet need for tools that can infer multiple origins. Misclassification of such individuals can lead to incorrect and costly misinterpretations of genomic data, primarily in disease studies and drug trials. We present an advanced tool to infer ancestry that can identify the biogeographic origins of highly mixed individuals. reAdmix can incorporate individual's knowledge of ancestors (e.g. having some ancestors from Turkey or a Scottish grandmother). reAdmix is an online tool available at http://chcb.saban-chla.usc.edu/reAdmix/. |
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Geographical breakdown
Country | Count | As % |
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United States | 1 | 25% |
Unknown | 3 | 75% |
Demographic breakdown
Type | Count | As % |
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Scientists | 2 | 50% |
Members of the public | 2 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Philippines | 1 | 3% |
United States | 1 | 3% |
Unknown | 30 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 8 | 25% |
Student > Ph. D. Student | 6 | 19% |
Student > Bachelor | 3 | 9% |
Professor > Associate Professor | 3 | 9% |
Student > Master | 2 | 6% |
Other | 1 | 3% |
Unknown | 9 | 28% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 8 | 25% |
Agricultural and Biological Sciences | 6 | 19% |
Social Sciences | 3 | 9% |
Computer Science | 2 | 6% |
Immunology and Microbiology | 1 | 3% |
Other | 3 | 9% |
Unknown | 9 | 28% |