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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Adult classical glioblastoma with a BRAF V600E mutation
|
|---|---|
| Published in |
World Journal of Surgical Oncology, March 2015
|
| DOI | 10.1186/s12957-015-0521-x |
| Pubmed ID | |
| Authors |
Yoshinobu Takahashi, Toshiaki Akahane, Takahiro Sawada, Hidetoshi Ikeda, Akira Tempaku, Shigeru Yamauchi, Hiroshi Nishihara, Shinya Tanaka, Kazumi Nitta, Wataru Ide, Ikuo Hashimoto, Hajime Kamada |
| Abstract |
The B-Raf proto-oncogene serine/threonine kinase (B-Raf) is a member of the Raf kinase family. The BRAF V600E mutation occurs frequently in certain brain tumors such as pleomorphic xanthoastrocytoma, ganglioglioma, and pilocytic astrocytoma, and less frequently in epithelioid and giant cell glioblastoma. BRAF V600E mutation in these cases has been canonically detected using Sanger sequencing or immunohistochemistry but not with next-generation sequencing (NGS). Moreover, to our knowledge, there is no detailed report of the BRAF V600E mutation in an adult glioblastoma with classical histologic features (c-GBM). Therefore, we performed NGS analysis to determine the mutational status of BRAF of 13 glioblastomas (GBMs) (11 primary and 2 secondary cases) and detected one tumor harboring the BRAF V600E mutation. We report here the detection of the BRAF V600E mutation in a patient with c-GBM and describe the patient's clinical course as well as the results of histopathological analysis. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 3 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 1 | 3% |
| Unknown | 35 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 7 | 19% |
| Researcher | 7 | 19% |
| Student > Ph. D. Student | 6 | 17% |
| Student > Postgraduate | 3 | 8% |
| Student > Master | 3 | 8% |
| Other | 5 | 14% |
| Unknown | 5 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 10 | 28% |
| Biochemistry, Genetics and Molecular Biology | 7 | 19% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 8% |
| Neuroscience | 3 | 8% |
| Agricultural and Biological Sciences | 2 | 6% |
| Other | 3 | 8% |
| Unknown | 8 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 December 2023.
All research outputs
#7,046,566
of 25,371,288 outputs
Outputs from World Journal of Surgical Oncology
#196
of 2,145 outputs
Outputs of similar age
#75,688
of 274,518 outputs
Outputs of similar age from World Journal of Surgical Oncology
#7
of 117 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 2,145 research outputs from this source. They receive a mean Attention Score of 2.3. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 274,518 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 117 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.