Title |
The role of enteric hormone GLP-2 in the response of bone markers to a mixed meal in postmenopausal women with type 2 diabetes mellitus
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Published in |
Diabetology & Metabolic Syndrome, February 2015
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DOI | 10.1186/s13098-015-0006-7 |
Pubmed ID | |
Authors |
Laura S Girão Lopes, Rubens Prado Schwartz, Bruno Ferraz-de-Souza, Maria Elizabeth Rossi da Silva, Pedro Henrique Silveira Corrêa, Márcia Nery |
Abstract |
Type 2 diabetes mellitus (T2D) is a complex disease associated with several chronic complications, including bone fragility and high fracture risk due to mechanisms not yet fully understood. The influence of the gastrointestinal tract and its hormones on bone remodeling has been demonstrated in healthy individuals. Glucagon-like peptide 2 (GLP-2), an enteric hormone secreted in response to nutrient intake, has been implicated as a mediator of nutrient effects on bone remodeling. This study aimed to analyze the dynamics of bone resorption marker C-terminal telopeptide of type I collagen (CTX), bone formation marker osteocalcin, and GLP-2 in response to a mixed meal in diabetic postmenopausal women. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 44 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 11 | 25% |
Student > Bachelor | 7 | 16% |
Student > Ph. D. Student | 5 | 11% |
Researcher | 4 | 9% |
Student > Postgraduate | 3 | 7% |
Other | 7 | 16% |
Unknown | 7 | 16% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 23 | 52% |
Biochemistry, Genetics and Molecular Biology | 4 | 9% |
Nursing and Health Professions | 2 | 5% |
Agricultural and Biological Sciences | 2 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
Other | 3 | 7% |
Unknown | 9 | 20% |