Title |
Polymeric nanoparticle-encapsulated curcumin ("nanocurcumin"): a novel strategy for human cancer therapy
|
---|---|
Published in |
Journal of Nanobiotechnology, April 2007
|
DOI | 10.1186/1477-3155-5-3 |
Pubmed ID | |
Authors |
Savita Bisht, Georg Feldmann, Sheetal Soni, Rajani Ravi, Collins Karikar, Amarnath Maitra, Anirban Maitra |
Abstract |
Curcumin, a yellow polyphenol extracted from the rhizome of turmeric (Curcuma longa), has potent anti-cancer properties as demonstrated in a plethora of human cancer cell line and animal carcinogenesis models. Nevertheless, widespread clinical application of this relatively efficacious agent in cancer and other diseases has been limited due to poor aqueous solubility, and consequently, minimal systemic bioavailability. Nanoparticle-based drug delivery approaches have the potential for rendering hydrophobic agents like curcumin dispersible in aqueous media, thus circumventing the pitfalls of poor solubility. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Venezuela, Bolivarian Republic of | 2 | 33% |
United States | 1 | 17% |
Italy | 1 | 17% |
Unknown | 2 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 5 | 83% |
Practitioners (doctors, other healthcare professionals) | 1 | 17% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 10 | 1% |
United States | 2 | <1% |
France | 2 | <1% |
Vietnam | 1 | <1% |
Brazil | 1 | <1% |
Germany | 1 | <1% |
Canada | 1 | <1% |
Switzerland | 1 | <1% |
Spain | 1 | <1% |
Other | 1 | <1% |
Unknown | 695 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 162 | 23% |
Student > Master | 110 | 15% |
Researcher | 67 | 9% |
Student > Bachelor | 66 | 9% |
Student > Doctoral Student | 39 | 5% |
Other | 136 | 19% |
Unknown | 136 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 131 | 18% |
Chemistry | 104 | 15% |
Pharmacology, Toxicology and Pharmaceutical Science | 82 | 11% |
Biochemistry, Genetics and Molecular Biology | 63 | 9% |
Medicine and Dentistry | 60 | 8% |
Other | 125 | 17% |
Unknown | 151 | 21% |