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Differential expression of pro-inflammatory cytokines IL-15Ralpha, IL-15, IL-6 and TNFalpha in synovial fluid from Rheumatoid arthritis patients

Overview of attention for article published in BMC Musculoskeletal Disorders, March 2015
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Mentioned by

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2 tweeters

Citations

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16 Dimensions

Readers on

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40 Mendeley
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Title
Differential expression of pro-inflammatory cytokines IL-15Ralpha, IL-15, IL-6 and TNFalpha in synovial fluid from Rheumatoid arthritis patients
Published in
BMC Musculoskeletal Disorders, March 2015
DOI 10.1186/s12891-015-0516-3
Pubmed ID
Authors

Alicia Santos Savio, Ana Cecilia Machado Diaz, Araceli Chico Capote, Jamilet Miranda Navarro, Yunier Rodríguez Alvarez, Ricardo Bringas Pérez, Miguel Estévez del Toro, Gerardo E Guillen Nieto

Abstract

Pro-inflammatory cytokines are directly implicated in the pathogenesis of Rheumatoid arthritis (RA). Variable clinical response to cytokine targeted therapies as TNFalpha and IL-6, strongly highlights the heterogeneity of inflammatory process in RA. Another cytokine, IL-15 has also been related to the inflammatory process in RA. Recently we described for the first time, the presence of its specific receptor, IL-15Ralpha, in synovial fluid (SF). The aim of this work was to compare the expression profile of IL-15Ralpha, its ligand IL-15, TNFalpha and IL-6 and how these cytokines are correlated in SF from RA patients taking as a reference Osteoarthritis (OA), an articular but not autoinmmune disease.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
Unknown 39 98%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 6 15%
Student > Ph. D. Student 5 13%
Student > Bachelor 4 10%
Researcher 4 10%
Student > Doctoral Student 3 8%
Other 9 23%
Unknown 9 23%
Readers by discipline Count As %
Medicine and Dentistry 11 28%
Agricultural and Biological Sciences 5 13%
Biochemistry, Genetics and Molecular Biology 4 10%
Immunology and Microbiology 3 8%
Sports and Recreations 2 5%
Other 9 23%
Unknown 6 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 March 2015.
All research outputs
#6,221,641
of 8,605,940 outputs
Outputs from BMC Musculoskeletal Disorders
#1,541
of 2,141 outputs
Outputs of similar age
#131,471
of 205,423 outputs
Outputs of similar age from BMC Musculoskeletal Disorders
#45
of 67 outputs
Altmetric has tracked 8,605,940 research outputs across all sources so far. This one is in the 24th percentile – i.e., 24% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,141 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.0. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 205,423 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 67 others from the same source and published within six weeks on either side of this one. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.