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Pichia pastoris regulates its gene-specific response to different carbon sources at the transcriptional, rather than the translational, level

Overview of attention for article published in BMC Genomics, March 2015
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (53rd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (57th percentile)

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Citations

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Title
Pichia pastoris regulates its gene-specific response to different carbon sources at the transcriptional, rather than the translational, level
Published in
BMC Genomics, March 2015
DOI 10.1186/s12864-015-1393-8
Pubmed ID
Authors

Roland Prielhofer, Stephanie P Cartwright, Alexandra B Graf, Minoska Valli, Roslyn M Bill, Diethard Mattanovich, Brigitte Gasser

Abstract

The methylotrophic, Crabtree-negative yeast Pichia pastoris is widely used as a heterologous protein production host. Strong inducible promoters derived from methanol utilization genes or constitutive glycolytic promoters are typically used to drive gene expression. Notably, genes involved in methanol utilization are not only repressed by the presence of glucose, but also by glycerol. This unusual regulatory behavior prompted us to study the regulation of carbon substrate utilization in different bioprocess conditions on a genome wide scale.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 223 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 3 1%
Mexico 2 <1%
United Kingdom 1 <1%
Germany 1 <1%
India 1 <1%
Japan 1 <1%
Unknown 214 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 54 24%
Researcher 35 16%
Student > Master 34 15%
Student > Bachelor 22 10%
Student > Postgraduate 9 4%
Other 24 11%
Unknown 45 20%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 83 37%
Agricultural and Biological Sciences 58 26%
Engineering 14 6%
Chemical Engineering 7 3%
Pharmacology, Toxicology and Pharmaceutical Science 3 1%
Other 11 5%
Unknown 47 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 April 2015.
All research outputs
#13,080,280
of 22,794,367 outputs
Outputs from BMC Genomics
#4,720
of 10,648 outputs
Outputs of similar age
#119,745
of 259,195 outputs
Outputs of similar age from BMC Genomics
#124
of 290 outputs
Altmetric has tracked 22,794,367 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 10,648 research outputs from this source. They receive a mean Attention Score of 4.7. This one has gotten more attention than average, scoring higher than 55% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 259,195 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.
We're also able to compare this research output to 290 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.